Pickard, Ben - University of Strathclyde - Strathclyde Institute of Pharmacy & Biomedical Sciences

个人简介

Ben Pickard obtained a BSc in Biochemistry from Imperial College London (1992), and a PhD from the University of Edinburgh (1996). Before coming to the University of Strathclyde, he worked at the Babraham Institute, Cambridge on factors regulating DNA methylation, and at the Molecular Medicine Centre, Edinburgh, identifying genetic risk factors for common psychiatric illnesses such as schizophrenia, bipolar disorder and major depression.

研究领域

The role of the NPAS3 and ABCA13 genes in psychiatric illness Metabolomic markers of mental illness A novel stem cell type, and it potential use in research and therapeutics A new gene trap-based mutation screening methodology to identify genes participating in specific aspects of cell function or response to drug treatment. Functional genetics of neuroinflammation and pathogen infection Oxidative stress biology Telomere manipulation to produce new cell lines for research Environmental factors influencing epigenetic marks on the genome

近期论文

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Brain changing tubers : gene expression changes following mediaeval tuber consumptionWoods N, Gebril A, Simpson Ann, Iannetta Ppm, Kenicer G, Tate R J, Pickard B, Gray A I, Ferro V APlanta Medica Vol 81, pp. S1-S381, (2016)http://dx.doi.org/10.1055/s-0036-1596241 Specialised information processing deficits and distinct metabolomic profiles following TM-domain disruption of Nrg1O'Tuathaigh CMP, Mathur N, O'Callaghan MJ, MacIntyre L, Harvey R, Lai D, Waddington JL, Pickard BS, Watson DG, Moran PMSchizophrenia Bulletin, (2016) The EpiTect Methyl qPCR Assay as novel age estimation method in forensic biologyMawlood Shakhawan K., Dennany Lynn, Watson Nigel, Pickard Benjamin S.Forensic Science International Vol 264, pp. 132-138, (2016)http://dx.doi.org/10.1016/j.forsciint.2016.03.047 Metabolomic Profiling of Post-Mortem Brain Reveals Changes in Amino Acid and Glucose Metabolism in Mental Illness Compared with ControlsZhang Rong, Zhang Tong, Ali Ali Muhsen, Al Washih Mohammed, Pickard Benjamin, Watson David G.Computational and Structural Biotechnology Journal Vol 14, pp. 106-116, (2016)http://dx.doi.org/10.1016/j.csbj.2016.02.003 Quantification of global mitochondrial DNA methylation levels and inverse correlation with age at two CpG sitesMawlood Shakhawan K., Dennany Lynn, Watson Nigel, Dempster John, Pickard Benjamin S.Aging Vol 8, pp. 636-641, (2016) Enhanced gene expression in the brain following intravenous administration of lactoferrin-bearing polypropylenimine dendriplexSomani Sukrut, Robb Gillian, Pickard Benjamin S., Dufes ChristineJournal of Controlled Release Vol 217, pp. 235-242, (2015)http://dx.doi.org/10.1016/j.jconrel.2015.09.003