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Parasite excretory-secretory products and their effects on metabolic syndromeCrowe Jenny, Lumb Felicity E., Harnett Margaret M., Harnett WilliamParasite Immunology, (2017)http://dx.doi.org/10.1111/pim.12410
Testing small molecule analogues of acanthocheilonema viteae immunomodulator ES-62 against clinically relevant allergensJanicova L., Rzepecka J., Rodgers D.T., Doonan J., Bell K., Lumb F.E., Suckling C.J., Harnett M.M., Harnett W.Parasite Immunology Vol 38, pp. 340-351, (2016)http://dx.doi.org/10.1111/pim.12322
The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62Bell Kara S., Al-Riyami Lamyaa, Lumb Felicity E., Britton Graham J., Poole Alastair W., Williams Chris M., Braun Ursula, Leitges Michael, Harnett Margaret M., Harnett WilliamImmunology Letters Vol 168, pp. 31-40, (2015)http://dx.doi.org/10.1016/j.imlet.2015.09.001
Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasomeRzepecka Justyna, Pineda Miguel A., Al-Riyami Lamyaa, Rodgers David T., Huggan Judith K., Lumb Felicity E., Khalaf Abedawn I., Meakin Paul J., Corbet Marlene, Ashford Michael L., Suckling Colin J., Harnett Margaret M., Harnett WilliamJournal of Autoimmunity Vol 60, pp. 59-73, (2015)http://dx.doi.org/10.1016/j.jaut.2015.04.005
The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr miceRodgers David T., McGrath Mairi A., Pineda Miguel A., Al-Riyami Lamyaa, Rzepecka Justyna, Lumb Felicity, Harnett William, Harnett Margaret M.Arthritis and Rheumatology Vol 67, pp. 1023-1035, (2015)http://dx.doi.org/10.1002/art.39004
ES-62, a therapeutic anti-inflammatory agent evolved by the filarial nematode Acanthocheilonema viteaePineda Miguel A., Lumb Felicity, Harnett Margaret M., Harnett WilliamMolecular and Biochemical Parasitology Vol 194, pp. 1-8, (2014)http://dx.doi.org/10.1016/j.molbiopara.2014.03.003