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Hypertension linked to PDE3A activationHouslay MilesNature Genetics Vol 47, pp. 562-563, (2015)http://dx.doi.org/10.1038/ng.3316
Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domainsBolger Graeme B., Dunlop Allan J., Meng Dong, Day Jon P., Klussmann Enno, Baillie George S., Adams David R., Houslay Miles D.Cellular Signalling Vol 27, pp. 756-769, (2015)http://dx.doi.org/10.1016/j.cellsig.2014.12.009
The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cellsHenderson D J P, Byrne A, Dulla K, Jenster G, Hoffmann R, Baillie G S, Houslay M DBritish Journal of Cancer Vol 110, pp. 1278-1287, (2014)http://dx.doi.org/10.1038/bjc.2014.22
Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1αLe Moan Natacha, Houslay Daniel, Christian Frank, Houslay Miles, Akassoglou KaterinaMolecular Cell Vol 44, pp. 476-490, (2011)http://dx.doi.org/10.1016/j.molcel.2011.08.033
DISC1-dependent switch from progenitor proliferation to migration in the developing cortexIshizuka Koko, Kamiya Atsushi, Oh Edwin, Kanki Hiroaki, Seshadri Saurav, Robinson Jon, Murdoch Hannah, Dunlop Allan, Kubo Ken-ichiro, Furukori Keiko, Huang Beverly, Zeledon Mariela, Hayashi-Takagi Ariko, Okano Hideyuki, Nakajima Kazunori, Houslay Miles, Katsanis Nicholas, Sawa AkiraNature Vol 473, pp. 92-96, (2011)http://dx.doi.org/10.1038/nature09859
Sleep deprivation impairs cAMP signalling in the hippocampusVecsey Christopher, Baillie George, Jaganath Devan, Havekes Robbert, Daniels Andrew, Wimmer Mathieu, Huang Ted, Brown Kim, Li Xiang-Yao, Descalzi Giannina, Kim Susan, Chen Tao, Shang Yu-Ze, Zhuo Min, Houslay Miles, Abel TedNature Vol 461, pp. 1122-1125, (2009)http://dx.doi.org/10.1038/nature08488