Dufès, Christine - University of Strathclyde - Strathclyde Institute of Pharmacy & Biomedical Sciences

个人简介

Dr Christine Dufès is a Senior Lecturer (Associate Professor) at the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS). She teaches on the Master of Pharmacy and on various MSc / MRes postgraduate degrees. Christine obtained a Doctorate in Pharmacy (with Distinction and congratulations of the Jury, 1997) and a PhD (with a European Label, Distinction and congratulations of the Jury, 2002) from the University of Poitiers (France). After four years as a post-doctoral researcher at the Cancer Research UK Beatson Laboratories in Glasgow, she was appointed as a Lecturer at SIPBS in 2006, obtained fellowship of the Higher Education Academy in 2007 and became a Senior Lecturer in 2012. Christine has been awarded the Biochemical Journal Young Investigator Award (2009) and the Tom Gibson Memorial Award (2012) for her research, in addition to the Best Overall Strathclyde Teaching Excellence Award (2013) for her teaching. She sits on the editorial boards for 18 journals.

研究领域

Design and development of novel tumour-targeted anti-cancer nanomedicines. Design and development of novel nanomedicines able to reach the brain after intravenous administration, with the ultimate aim to facilitate drug and gene delivery to brain tumours and neurodegenerative disorders.

近期论文

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Tumor regression after intravenous administration of targeted vesicles entrapping the vitamin E α-tocotrienolKarim Reatul, Somani Sukrut, Al Robaian Majed, Mullin Margaret, Amor Rumelo, McConnell Gail, Dufès ChristineJournal of Controlled Release Vol 246, pp. 79-87, (2017)http://dx.doi.org/10.1016/j.jconrel.2016.12.014 Enhanced gene expression in the brain following intravenous administration of lactoferrin-bearing polypropylenimine dendriplexSomani Sukrut, Robb Gillian, Pickard Benjamin S., Dufes ChristineJournal of Controlled Release Vol 217, pp. 235-242, (2015)http://dx.doi.org/10.1016/j.jconrel.2015.09.003 Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexesLim Li Ying, Koh Pei Yin, Somani Sukrut, Al Robaian Majed, Karim Reatul, Yean Yi Lyn, Mitchell Jennifer, Tate Rothwelle J., Edrada-Ebel RuAngelie, Blatchford David R., Mullin Margaret, Dufès ChristineNanomedicine: Nanotechnology, Biology and Medicine Vol 11, pp. 1445-1454, (2015)http://dx.doi.org/10.1016/j.nano.2015.04.006 Transferrin-bearing dendrimers for cancer therapy : an updateSomani Sukrut, Dufes ChristineNanomedicine Vol 10, pp. 2125-2127, (2015)http://dx.doi.org/10.2217/nnm.15.93 Anti-cancer efficacy of intravenously administered tumor-targeted vesicles entrapping tocotrienolFu Ju Yen, Dufès ChristinePharmaceutical Nanotechnology Vol 2, pp. 172-181, (2015)http://dx.doi.org/10.2174/2211738503666150119231232 Applications of dendrimers for brain delivery and cancer therapySomani Sukrut, Dufès ChristineNanomedicine Vol 9, pp. 2403-2414 , (2014)http://dx.doi.org/10.2217/nnm.14.130