Currie, Susan - University of Strathclyde - Strathclyde Institute of Pharmacy & Biomedical Sciences

个人简介

Susan Currie obtained her PhD in Biochemistry (cellular signalling and molecular pharmacology) from the University of Glasgow in 1992 then spent two years at Lilly Research Laboratories, USA, where she studied the role of phospholipase A² in mast cell activation. She returned to the University of Glasgow in 1994 to join the then newly formed Clinical Research Initiative in heart disease and became a founder member of the school of cardiovascular studies in Glasgow. During this time she progressed from postdoctoral researcher to Principal Investigator examining the role of Calcium/calmodulin protein kinase ll (CaMKll) in cardiac hypertrophy and heart failure. She moved to the University of Strathclyde in 2005 as a Lecturer in Physiology & Pharmacology and established an independent cardiovascular signalling research group with principal interests in CaMKll modulation of cardiac calcium handling and cardiac inflammation. CaMKll as a therapeutic target in cardiac disease remains a key focus of research and characterising the actions of this enzyme in both healthy and diseased adult cardiac myocytes and cardiac fibroblasts is ongoing.

近期论文

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Changes in IP3 receptor expression and function in aortic smooth muscle of atherosclerotic miceEwart Marie-ann, Ugusman Azizah, Vishwanath Anisha, Almabrouk Tarek, Alganga Husman, Katwan Omar, Hubanova Pavlina , Currie Susan, Kennedy SimonJournal of Vascular Research, (2017) Investigating cobalt toxicity in the context of joint replacement patients - cobalt uptake in primary cardiac fibroblasts and in 3T3 cellsLaovitthayanggoon Sarunya, Grant M. Helen, Henderson Catherine J., Tate Rothwelle J., Currie SusanApplied in Vitro Toxicology Vol 2, (2016)http://dx.doi.org/10.1089/aivt.2016.29007.abstracts Effects of trans-isoferulic acid and gallic acid on cardiac contractility : is there a role for CaMKII?Currie Susan, Qim Kimberley, Mum Hui , Campbell Sara, MacKenzie Graeme, Mohd Salleh Mohd Hanif, Chellapan Dinesh, Candasamy MayurenInternational Journal of Molecular Medicine Vol 38, (2016) Calcium/calmodulin-dependent protein kinase II - does ageing mirror disease?McCluskey Claire, Salleh Hanif, Currie SusanFASEB Journal Vol 30, (2016) Inositol trisphosphate receptor contribution to ventricular cardiac fibroblast function in healthy and hypertrophied mouse heartsCurrie Susan, Martin Tamara Patricia, Salleh Hanif, McCluskey Claire, Bushell Trevor JohnFASEB Journal Vol 30, (2016) Cobalt cardiotoxicity - effects on the contractile and non-contractile cells of the heartLaovitthayanggoon Sarunya, Tate Rothwelle, Currie Susan, Grant Mary HelenFASEB Journal Vol 30, (2016)