个人简介
Allan studied Chemistry at The University of Strathclyde and received his MSci in 2004. He then undertook PhD research under the supervision of Prof. Billy Kerr at Strathclyde. In 2008, he joined the laboratories of Prof. David W. C. MacMillan at Princeton University as a Lindemann Postdoctoral Fellow. Allan was appointed as a Lecturer at the University of Strathclyde in October 2010. Following an EPSRC Knowledge Transfer Secondment to GlaxoSmithKline, Stevenage, Allan returned to the Department in August 2011.
研究领域
Our research interests are in the area of organic synthesis and methodology, particularly in the area of catalysis.
Synthesis and functionalisation of heterocycles
Fluorine chemistry
Transition metal-catalysed processes
Sustainable synthesis and purification
近期论文
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Amidation of unactivated ester derivatives mediated by trifluoroethanolMcPherson Christopher G., Caldwell Nicola, Jamieson Craig, Simpson Iain, Watson Allan J. B.Organic and biomolecular chemistry, (2017)http://dx.doi.org/10.1039/C7OB00593H
Determining the origin of rate-independent chemoselectivity in CuAAC reactions : an alkyne-specific shift in rate-determining stepSeath Ciaran P., Burley Glenn A., Watson Allan J. B.Angewandte Chemie Vol 56, pp. 3314-3318, (2017)http://dx.doi.org/10.1002/anie.201612288
Rational design of autotaxin inhibitors by structural evolution of endogenous modulatorsKeune Willem-Jan, Potjewyd Frances, Heidebrecht Tatjana, Salgado-Polo Fernando, Macdonald Simon J. F., Chelvarajan Lakshman, Abdel Latif Ahmed, Soman Sony, Morris Andrew J., Watson Allan J. B., Jamieson Craig, Perrakis AnastassisJournal of Medicinal Chemistry Vol 60, pp. 2006-2017, (2017)http://dx.doi.org/10.1021/acs.jmedchem.6b01743
Emergence of small molecule non-RGD-mimetic inhibitors for RGD integrinsMiller Lisa M., Pritchard John M., Macdonald Simon J. F., Jamieson Craig, Watson Allan J. B.Journal of Medicinal Chemistry, (2017)http://dx.doi.org/10.1021/acs.jmedchem.6b01711
Structure-activity relationships of small molecule autotaxin inhibitors with a discrete binding modeMiller Lisa M., Keune Willem-Jan, Castagna Diana, Young Louise C., Duffy Emma L., Potjewyd Frances, Salgado-Polo Fernando, Garcia Paloma Engel, Semaan Dima, Pritchard John M., Perrakis Anastassis, Macdonald Simon J. F., Jamieson Craig, Watson Allan J. B.Journal of Medicinal Chemistry Vol 60, pp. 722-748, (2017)http://dx.doi.org/10.1021/acs.jmedchem.6b01597
Chemoselective Suzuki-Miyaura cross-coupling via kinetic transmetallationFyfe James W. B., Fazakerley Neal J., Watson Allan J. B.Angewandte Chemie, (2016)