Gibson, Colin - University of Strathclyde - Department of Pure & Applied Chemistry

个人简介

Colin Gibson was born in the Scottish border town of Hawick, famous for its rugby football and knitting industry. The family moved to Godalming near Guildford in deepest Southern England when he was ten years old. He went to Southampton University for his B.Sc. studies and stayed there to carry out Ph.D research with Professor Ray Baker, FRS. This work involved initially the analysis of insect hormones but mainly involved the total synthesis of a number of natural products. After Southampton, Colin was awarded a University of Melbourne research fellowship in Australia. Here he spent a very enjoyable two years working with Professor Don Cameron on the synthesis of quinone natural products as well as visiting relatives. On returning to the UK he took up a post doctoral research associateship with Professor Sir Alan Battersby, FRS at the University Chemical Laboratory in Cambridge on the synthesis of putative intermediates in vitamin B12 biosynthesis. This was followed by a Senior Research Fellowship at Christ's College, Cambridge. The heady heights of Cambridge were followed by short interlude at Surrey University as a member of Faculty. In 1991 he made the move back to Scotland and joined the Strathclyde Chemistry Department. In his spare time he enjoys watching Hawick RFC playing, drinking wine, cycling (occasional mountain biking) and walking, particularly on the Island of Arran

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A method for the analysis of sugars in biological systems using reductive amination in combination with hydrophilic interaction chromatography and high resolution mass spectrometryBawazeer Sami, Muhsen Ali Ali, Alhawiti Aliyah, Khalaf Abedawn, Gibson Colin, Tusiimire Jonans, Watson David G.Talanta Vol 166, pp. 75-80, (2017)http://dx.doi.org/10.1016/j.talanta.2017.01.038 Structure based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1Khalaf Abedawn I, Huggan Judith, Suckling Colin J, Gibson Colin L, Stewart Kirsten, Giordani Federica , Barrett Michael P., Wong Pui Ee, Barrack Keri L , Hunter William NJournal of Medicinal Chemistry Vol 57, pp. 6479-6494, (2014)http://dx.doi.org/10.1021/jm500483b Communication between the zinc and tetrahydrobiopterin binding sites in nitric oxide synthaseChreifi Georges, Li Huiying, McInnes Craig, Gibson Colin, Suckling Colin, Poulos Thomas LBiochemistry, (2014)http://dx.doi.org/10.1021/bi5003986 Tetrahydrobiopterin and electron transfer in NO synthaseDaff Simon, Gazur Ben, Papale Davide, McInnes Craig, Morthala Raghavendar R., Gibson Colin L., Suckling Colin J.Nitric Oxide: Biology and Chemistry Vol 27, pp. S5-S5, (2012)http://dx.doi.org/10.1016/j.niox.2012.04.019 23rd International Conference on Heterocyclic Chemistry (ICHC-23), Glasgow, UK, 31 July-4 August 2011Gibson ColinPure and Applied Chemistry Vol 84, pp. iv-iv, (2012) Diversity oriented synthesis : substitution at C5 in unreactive pyrimidines by Claisen rearrangement and reactivity in nucleophilic substitution at C2 and C4 in pteridines and pyrido[2,3-d]pyrimidinesAdcock Jonathan Paul, Gibson Colin, Huggan Judith, Suckling ColinTetrahedron Vol 67, pp. 3226-3237, (2011)http://dx.doi.org/10.1016/j.tet.2011.03.011