Faulds, Karen - University of Strathclyde - Department of Pure & Applied Chemistry

研究领域

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences. SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research. Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR. Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample. This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure

近期论文

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Detection of cortisol in serum using quantitative resonance Raman spectroscopyGracie Kirsten, Pang Susan, Jones Gerwyn M., Faulds Karen, Braybrook Julian, Graham DuncanAnalytical Methods, (2017)http://dx.doi.org/10.1039/C6AY03296F Silver colloids as plasmonic substrates for direct label-free surface-enhanced Raman scattering analysis of DNATorres-Nu?ez A., Faulds K., Graham D., Alvarez-Puebla R. A., Guerrini L.Analyst Vol 141, pp. 5170-5180, (2016)http://dx.doi.org/10.1039/c6an00911e Sensitive SERS nanotags for use with 1550 nm (retina-safe) laser excitationKearns Hayleigh, Bedics Matthew A., Shand Neil C., Faulds Karen, Detty Michael R., Graham DuncanAnalyst Vol 141, pp. 5062-5065, (2016)http://dx.doi.org/10.1039/C5AN02662H Thermoresponsive polymer micropatterns fabricated by dip-pen nanolithography for a highly controllable substrate with potential cellular applicationsLaing Stacey, Suriano Raffaella, Lamprou Dimitrios A., Smith Carol-Anne, Dalby Matthew J., Mabbott Samuel, Faulds Karen, Graham DuncanACS Applied Materials and Interfaces Vol 8, pp. 24844–24852, (2016)http://dx.doi.org/10.1021/acsami.6b03860 Detection of potentially toxic metals by SERS using salen complexesDocherty Julie Ann, Mabbott Samuel, Smith W E, Faulds Karen, Davidson C M, Reglinski J, Graham DuncanAnalyst, (2016)http://dx.doi.org/10.1039/C6AN01584K Elucidation of the bonding of a near infrared dye to hollow gold nanospheres : a chalcogen tripodKearns Hayleigh, Sengupta S, Ramos Sasselli Ivan, Bromley L, Faulds Karen, Tuttle Christopher, Bedics Matthew A., Detty Michael R., Verlarde Luis, Graham Duncan, Smith W. EwenChemical Science Vol 7, pp. 5160-5170, (2016)http://dx.doi.org/10.1039/C6SC00068A