Gunn-Moore, Frank - University of St Andrews

个人简介

BSc. Biological Sciences, University of Edinburgh PhD. Department of Biochemistry, University of Cambridge Post-doctoral, Department of Biochemistry, University of Bristol and Department of Pre-clinical Veterinary Sciences, University of Edinburgh Lecturer, Senior Lecturer, Reader, Professor, School of Biology, University of St Andrews Invited and elected Fellow of the Royal Society of Biology

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Aitken, L, Baillie, G, Pannifer, A, Morrison, A, Jones, PS, Smith, TK, McElroy, SP & Gunn-Moore, FJ 2017, 'In vitro assay development and HTS of small molecule human ABAD/17β-HSD10 inhibitors as therapeutics in Alzheimer’s Disease' SLAS Discovery, vol In press. DOI: 10.1177/247255521769796 Hroch, L, Guest, P, Benek, O, Soukup, O, Janockova, J, Dolezal, R, Kuca, K, Aitken, L, Smith, TK, Gunn-Moore, F, Zala, D, Ramsay, RR & Musilek, K 2017, 'Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment' Bioorganic & Medicinal Chemistry, vol 25, no. 3, pp. 1143-1152. DOI: 10.1016/j.bmc.2016.12.029 Benek, O, Hroch, L, Aitken, L, Dolezal, R, Guest, P, Benkova, M, Soukup, O, Musil, K, Hughes, R, Kuca, K, Smith, TK, Gunn-Moore, F & Musilek, K 2017, '6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: design, synthesis and in vitro evaluation' Medicinal Chemistry, vol 13. DOI: 10.2174/157340641366170109142725 Tilston-Lunel, AM, Haley, K, Schlecht, N, Wang, Y, Chatterton, ALD, Moleirinho, SL, Watson, A, Hundal, H, Prystowsky, M, Gunn-Moore, FJ & Reynolds, PA 2016, 'Crumbs 3b promotes tight junctions in an ezrin-dependent manner in mammalian cells' Journal of Molecular Cell Biology, vol 8, no. 5, pp. 439-455. DOI: 10.1093/jmcb/MJW020 Mielenz, D & Gunn-Moore, FJ 2016, 'Physiological and pathophysiological functions of Swiprosin-1/EFhd2 in the nervous system' Biochemical Journal, vol 473, no. 16, pp. 2429-2437. DOI: 10.1042/BCJ20160168