近期论文

查看导师最新文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Aitken, L, Baillie, G, Pannifer, A, Morrison, A, Jones, PS, Smith, TK, McElroy, SP & Gunn-Moore, FJ 2017, 'In vitro assay development and HTS of small molecule human ABAD/17β-HSD10 inhibitors as therapeutics in Alzheimer’s Disease' SLAS Discovery, vol In press. DOI: 10.1177/247255521769796 Hroch, L, Guest, P, Benek, O, Soukup, O, Janockova, J, Dolezal, R, Kuca, K, Aitken, L, Smith, TK, Gunn-Moore, F, Zala, D, Ramsay, RR & Musilek, K 2017, 'Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment' Bioorganic & Medicinal Chemistry, vol 25, no. 3, pp. 1143-1152. DOI: 10.1016/j.bmc.2016.12.029 Benek, O, Hroch, L, Aitken, L, Dolezal, R, Guest, P, Benkova, M, Soukup, O, Musil, K, Hughes, R, Kuca, K, Smith, TK, Gunn-Moore, F & Musilek, K 2017, '6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: design, synthesis and in vitro evaluation' Medicinal Chemistry, vol 13. DOI: 10.2174/157340641366170109142725 Hroch, L, Benek, O, Guest, P, Aitken, L, Soukup, O, Janockova, J, Musil, K, Dohnal, V, Dolezal, R, Kuca, K, Smith, TK, Gunn-Moore, FJ & Musilek, K 2016, 'Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment' Bioorganic and Medicinal Chemistry Letters, vol 26, no. 15, pp. 3675-3678. DOI: 10.1016/j.bmcl.2016.05.087 Aitken, L, Quinn, SD, Perez-Gonzalez, DC, Samuel, IDW, Penedo-Esteiro, JC & Gunn-Moore, FJ 2016, 'Morphology-specific inhibition of β-amyloid aggregates by 17β-hydroxysteroid dehydrogenase type 10' ChemBioChem, vol 17, no. 11, pp. 1029-1037. DOI: 10.1002/cbic.201600081