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Genes and sex-specific behaviour in Drosophila melanogaster. Drosophila as a model of human mitochondrial disease, especially deafness. Drosophila as a model of human myotonic dystrophy

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Vartiainen, S., Chen, S., George, J., Tuomela, T., Luoto, K. R., O'Dell, K. M.C., and Jacobs, H. T. (2014) Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease. Disease Models and Mechanisms, 7(6), pp. 635-648. (doi:10.1242/dmm.016527) Fernández-Ayala, D.J.M., Chen, S., Kemppainen, E., O'Dell, K.M.C., and Jacobs, H.T. (2010) Gene expression in a drosophila model of mitochondrial disease. PLoS ONE, 5(1), e8549. (doi:10.1371/journal.pone.0008549) Kemppainen, E., Fernández-Ayala, D.J.M., Galbraith, L.C.A., O'Dell, K.M.C., and Jacobs, H.T. (2009) Phenotypic suppression of the Drosophila mitochondrial disease-like mutant tko25t by duplication of the mutant gene in its natural chromosomal context. Mitochondrion, 9(5), pp. 353-363. (doi:10.1016/j.mito.2009.07.002) Fernandez-Ayala, D.J.M. et al. (2009) Expression of the ciona intestinalis alternative oxidase (aox) in drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metabolism, 9(5), pp. 449-460. (doi:10.1016/j.cmet.2009.03.004) Lindsay, H.A., Baines, R., French-Constant, R., Lilley, K., Jacobs, H.T., and O'Dell, K.M.C. (2008) The dominant cold-sensitive out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic. Genetics, 180(2), pp. 873-884. (doi:10.1534/genetics.108.090951) Jacobs, H.T., Fernandez-Ayala, D.J.M., Manjiry, S., Kemppainen, E., Toivonen, J.M., and O'Dell, K.M. (2004) Mitochondrial disease in flies. Biochimica et Biophysica Acta: Bioenergetics, 1659, pp. 190-196. (doi:10.1016/j.bbabio.2004.07.004) O'Dell, K.M. (2003) The voyeurs' guide to Drosophila melanogaster courtship. Behavioural Processes, 64, pp. 211-223. (doi:10.1016/S0376-6357(03)00136-0) Toivonen, J.M., Manjiry, S., Touraille, S., Alziari, S., O'Dell, K.M., and Jacobs, H.T. (2003) Gene dosage and selective expression modify phenotype in a Drosophila model of human mitochondrial disease. Mitochondrion, 3, pp. 83-96. (doi:10.1016/S1567-7249(03)00077-1) Toivonen, J.M. et al. (2001) technical knockout, a Drosophila model of mitochondrial deafness. Genetics, 159, pp. 241-254.

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