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研究领域

Structure and function of unusual lipid binding proteins of free-living and parasitic nematodes Allergen proteins The evolution of viviparity in mammals The molecular biology and biochemistry of frog nest foams

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Brandani, G. B., Vance, S. J., Schor, M., Cooper, A., Kennedy, M. W., Smith, B. O., MacPhee, C. E., and Cheung, D. L. (2017) Adsorption of the natural protein surfactant Rsn-2 onto liquid interfaces. Physical Chemistry Chemical Physics, (doi:10.1039/C6CP07261E) (PMID:28289744) (Early Online Publication) Cooper, A., Vance, S., Smith, B. O., and Kennedy, M. W. (2017) Frog foams and natural protein surfactants. Colloids and Surfaces A: Physicochemical and Engineering Aspects, (In Press) Acevedo, N., Bornacelly, A., Mercado, D., Unneberg, P., Mittermann, I., Valenta, R., Kennedy, M., Scheynius, A., and Caraballo, L. (2016) Genetic variants in CHIA and CHI3L1 are associated with the IgE response to the Ascaris resistance marker ABA-1 and the birch pollen allergen Bet v 1. PLoS ONE, 11(12), e0167453. (doi:10.1371/journal.pone.0167453) (PMID:27977724) Zhang, T., Watson, D. G., Zhang, R., Hou, R., Loeffler, I. K., and Kennedy, M. W. (2016) Changeover from signalling to energy-provisioning lipids during transition from colostrum to mature milk in the giant panda (Ailuropoda melanoleuca). Scientific Reports, 6, 36141. (doi:10.1038/srep36141) (PMID:27808224) (PMCID:PMC5093549) Satitsuksanoa, P. et al. (2016) The minor house dust mite allergen Der p 13 is a fatty acid binding protein and an activator of a TLR2-mediated innate immune response. Allergy, 71(10), pp. 1425-1434. (doi:10.1111/all.12899) (PMID:27018864) Vance, S. J., Desai, V., Smith, B. O., Kennedy, M. W., and Cooper, A. (2016) Aqueous solubilization of C60 fullerene by natural protein surfactants, latherin and ranaspumin-2. Biophysical Chemistry, 214-15, pp. 27-32. (doi:10.1016/j.bpc.2016.05.003) (PMID:27214760) (PMCID:PMC4906151) Burns, T.J., Davidson, H., and Kennedy, M.W. (2016) Large-scale investment in the excavation and ‘camouflaging’ phases by nesting leatherback turtles (Dermochelys coriacea). Canadian Journal of Zoology, 94(6), pp. 443-448. (doi:10.1139/cjz-2015-0240) Zhang, T., Zhang, R., Zhang, L., Zhang, Z., Hou, R., Wang, H., Loeffler, I. K., Watson, D. G., and Kennedy, M. W. (2015) Changes in the milk metabolome of the Giant Panda (Ailuropoda melanoleuca) with time after birth: three phases in early lactation and progressive individual differences. PLoS ONE, 10(12), e0143417. (doi:10.1371/journal.pone.0143417) (PMID:26630345) (PMCID:PMC4668050) Griffiths, K., Rong, H., Wang, H., Zhang, Z., Zhang, T., Watson, D. G., Burchmore, R., Loeffler, I.K., and Kennedy, M. (2015) Prolonged transition time between colostrum and mature milk in a bear, the giant panda, Ailuropoda melanoleuca. Royal Society Open Science, 2, 150395. (doi:10.1098/rsos.150395) Ahumada, V. et al. (2015) IgE responses to ascaris and mite tropomyosins are risk factors for asthma. Clinical and Experimental Allergy, 45(7), pp. 1189-1200. (doi:10.1111/cea.12513) (PMID:25702830) Burns, T. J., McCafferty, D. J., and Kennedy, M. W. (2015) Core and body surface temperatures of nesting leatherback turtles (Dermochelys coriacea). Journal of Thermal Biology, 51, pp. 15-22. (doi:10.1016/j.jtherbio.2015.03.001) (PMID:25965013) Franchini, G. R., Pórfido, J. L., Ibá?ez Shimabukuro, M., Rey Burusco, M. F., Bélgamo, J. A., Smith, B. O., Kennedy, M. W., and Córsico, B. (2015) The unusual lipid binding proteins of parasitic helminths and their potential roles in parasitism and as therapeutic targets. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 93, pp. 31-36. (doi:10.1016/j.plefa.2014.08.003) (PMID:25282399) Rey, B. M.F. et al. (2015) Diversity in the structures and ligand binding sites of nematode fatty acid and retinol binding proteins revealed by Na-FAR-1 from Necator americanus. Biochemical Journal, 471(3), pp. 403-414. (doi:10.1042/BJ20150068) (PMID:26318523) (PMCID:PMC4613501) Silva-álvarez, V., Franchini, G. R., Pórfido, J. L., Kennedy, M. W., Ferreira, A. M., and Córsico, B. (2015) Lipid-free Antigen B subunits from echinococcus granulosus: oligomerization, ligand binding, and membrane interaction properties. PLoS Neglected Tropical Diseases, 9(3), e0003552. (doi:10.1371/journal.pntd.0003552) (PMID:25768648) (PMCID:PMC4358968) Pooley, E. L., Kennedy, M. G., and Nager, R. G. (2014) Maternal inbreeding reduces parental care in the zebra finch, Taeniopygia guttata. Animal Behaviour, 97, pp. 153-163. (doi:10.1016/j.anbehav.2014.09.012) Ibá?ez-Shimabukuro, M., Rey-Burusco, M.F., Cooper, A., Kennedy, M. W., Córsico, B., and Smith, B. O. (2014) Resonance assignment of As-p18, a fatty acid binding protein secreted by developing larvae of the parasitic nematode Ascaris suum. Biomolecular NMR Assignments, 8(1), pp. 33-36. (doi:10.1007/s12104-012-9447-1) Vance, S. J., McDonald, R. E., Cooper, A., Kennedy, M. W., and Smith, B. O. (2014) Resonance assignments for latherin, a natural surfactant protein from horse sweat. Biomolecular NMR Assignments, 8(1), pp. 213-216. (doi:10.1007/s12104-013-9485-3) Rey-Burusco, M.F., Iba?ez-Shimabukuro, M., Cooper, A., Kennedy, M. W., Córsico, B., and Smith, B. O. (2014) 1H, 13C and 15N chemical shift assignments of Na-FAR-1, a helix-rich fatty acid and retinol binding protein of the parasitic nematode Necator americanus. Biomolecular NMR Assignments, 8(1), pp. 19-21. (doi:10.1007/s12104-012-9444-4) Roncada, P., Stipetic, L.H., Bonizzi, L., Burchmore, R.J.S., and Kennedy, M.W. (2013) Proteomics as a tool to explore human milk in health and disease. Journal of Proteomics, 88, pp. 47-57. (doi:10.1016/j.jprot.2013.04.008) Vance, S.J., McDonald, R.E., Cooper, A., Smith, B.O., and Kennedy, M.W. (2013) The structure of latherin, a surfactant allergen protein from horse sweat and saliva. Journal of the Royal Society: Interface, 10(85), Art. 20130453. (doi:10.1098/rsif.2013.0453) Gabrielsen, M., Rey-Burusco, M.F., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Kennedy, M.W., and Corsico, B. (2012) Two crystal forms of a helix-rich fatty acid- and retinol-binding protein, Na-FAR-1, from the parasitic nematodeNecator americanus. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68(7), pp. 835-838. (doi:10.1107/S1744309112023597) Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibá?ez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68, pp. 939-941. (doi:10.1107/S1744309112026553) Gabrielsen, M., Riboldi-Tunnicliffe, A., Ibá?ez-Shimabukuro, M., Griffiths, K., Roe, A.J., Cooper, A., Smith, B.O., Córsico, B., and Kennedy, M.W. (2012) Useable diffraction data from a multiple microdomain-containing crystal ofAscaris suumAs-p18 fatty-acid-binding protein using a microfocus beamline. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 68(8), pp. 939-941. (doi:10.1107/S1744309112026553) Porfido, J.L., Alvite, G., Silva, V., Kennedy, M.W., Esteves, A., and Corsico, B. (2012) Direct interaction between EgFABP1, a fatty acid binding protein from echinococcus granulosus, and phospholipid membranes. PLoS Neglected Tropical Diseases, 6(11), e1893. (doi:10.1371/journal.pntd.0001893) Kennedy, M.W. (2011) Latherin and other biocompatible surfactant proteins. Biochemical Society Transactions, 39(4), pp. 1017-1022. (doi:10.1042/BST0391017)

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