Gray, Joseph - University of Glasgow - School of Life Sciences

研究领域

Understanding and Exploiting Eukaryotic Signaling Mechanisms using Yeast as a Model System Nutrient Signaling: the TORC1 Pathway Morphogenesis and Stress: the Rho1 GTPase Pathway Synthetic Biology

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Evans, S., Burgess, K. E.V., and Gray, J. V. (2014) Recovery from Rapamycin: drug-insensitive activity of yeast target of rapamycin complex 1 (torc1) supports residual proliferation that dilutes rapamycin among progeny cells. Journal of Biological Chemistry, 289(38), pp. 26554-26565. (doi:10.1074/jbc.M114.589754) (PMID:25104356) (PMCID:PMC4176226) Krause, S., Cundell, M., Poon, P., McGhie, J., Johnston, G., Price, C., and Gray, J. (2012) Functional specialization of the yeast Rho1 GTP exchange factors. Journal of Cell Science, 125(11), pp. 2721-2731. (doi:10.1242/?jcs.100685) Krause, S. A., Cundell, M. J., Poon, P. P., McGhie, J., Johnston, G. C., Price, C., and Gray, J. V. (2012) Functional specialisation of yeast Rho1 GTP exchange factors. Journal of Cell Science, 125(11), pp. 2721-2731. (doi:10.1242/jcs.100685) (PMID:22344253) Gray, J.V., and Krause, S.A. (2009) Chapter 3 synthetic genetic interactions: allele dependence, uses, and conservation. Advances in Genetics, 66, pp. 61-84. (doi:10.1016/S0065-2660(09)66003-X) Krause, S.A., and Gray, J.V. (2009) The functional relationships underlying a synthetic genetic network. Communicative and Integrative Biology, 2(1), pp. 4-6. (doi:10.4161/cib.2.1.7298) Krause, S.A., Xu, H., and Gray, J.V. (2008) The synthetic genetic network around PKC1 identifies novel modulators and components of protein kinase C signaling in Saccharomyces cerevisiae. Eukaryotic Cell, 7(11), pp. 1880-1887. (doi:10.1128/EC.00222-08) Day, J.P., Wang, S.M., Allan, A.K., Kean, L., Davies, S.A., Gray, J.V., and Dow, J.A.T. (2008) Identification of two partners from the bacterial Kef exchanger family for the apical plasma membrane V-ATPase of Metazoa. Journal of Cell Science, 121(15), pp. 2612-2619. (doi:10.1242/jcs.033084) Gray, J.V., and Krause, S.A. (2007) Identifying in vivo pathways using genome-wide genetic networks. Biochemical Society Transactions, 35(Pt6), pp. 1538-1541. (doi:10.1042/BST0351538) (PMID:18031262) Stewart, M.S., Krause, S.A., McGhie, J., and Gray, J.V. (2007) Mpt5p, a stress tolerance- and lifespan-promoting PUF protein in Saccharomyces cerevisiae, acts upstream of the cell wall integrity pathway. Eukaryotic Cell, 6(2), pp. 262-270. Stewart, M.S., Krause, S.A., McGhie, J., and Gray, J.V. (2007) Mpt5p, a stress tolerance- and lifespan-promoting PUF protein in Saccharomyces cerevisiae, acts upstream of the cell wall integrity pathway. Eukaryotic Cell, 6(2), pp. 262-270. (doi:10.1128/EC.00188-06) Gray, J., Petsko, G., Johnston, G., Ringe, D., Singer, R., and Werner-Washburne, M. (2004) "Sleeping beauty": Quiescence in Saccharomyces cerevisiae. Microbiology and Molecular Biology Reviews, 68, 187-+. (doi:10.1128/MMBR.68.2.187-206.2004) Krause, S.A., and Gray, J.V. (2002) The protein kinase C pathway is required for viability in quiescence in Saccharomyces cerevisiae. Current Biology, 12, pp. 588-593. Rayner, T., Gray, J., and Thorner, J. (2002) Direct and novel regulation of cAMP-dependent protein kinase by Mck1p, a yeast glycogen synthase kinase-3. Journal of Biological Chemistry, 277, pp. 16814-16822. (doi:10.1074/jbc.M112349200) Trotter, E., Kao, C., Berenfeld, L., Botstein, D., Petsko, G., and Gray, J. (2002) Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae. Journal of Biological Chemistry, 277, pp. 44817-44825. (doi:10.1074/jbc.M204686200) Trotter, E.W., Berenfeld, L., Krause, S.A., Petsko, G.A., and Gray, J.V. (2001) Protein misfolding and temperature up-shift cause G(1) arrest via a common mechanism dependent on heat shock factor in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, 98(13), pp. 7313-7318. (doi:10.1073/pnas.121172998)