Campopiano, Dominic - University of Edinburgh

研究领域

Natural product biosynthesis, enzymology, protein structure, antibiotics, innate immunity enzyme inhibitors

近期论文

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Raman, M. C., Johnson, K. A., Yard, B. A., Lowther, J., Carter, L. G., Naismith, J. H. & Campopiano, D. J. The external-aldimine form of serine palmitoyltranserase; structural, kinetic and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics. J. Biol. Chem., 2009, 284, 17328-17339 Lowther, J., McMahon, S., Johnson, K. A., Yard, B. A., Carter, L. G Raman, M. C., Naismith, J. H. & Campopiano, D. J. Serine palmitoyltranserase displays a novel mechanism of cycloserine inhibition. Molecular Biosystems, 2010, 6, 1682-1693 Bhat, V. T., Caniard, A. M., Luksch, T., Brenk, R., Campopiano, D. J.,* & Greaney, M. F.* Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry. Nature Chemistry, 2010, 2, 490-497 Campopiano, D. J., Clarke, D. J., Polfer, N. C., Barran, P. E., Langley, R. J., Govan, J. R. W., Maxwell, A., & Dorin, J. R. Structure-activity relationships in defensin dimers. J. Biol. Chem., 2004, 279 (47), 48671-48679 Ortega, X. P., Cardona, S. T., Brown, A. R., Loutet, S. A., Flannagan, R. S., Campopiano, D. J., Govan, J. R. W., & Valvano, M. A. A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability. J. Bacteriol., 2007, 189, 3639-3644