SWAIN, Peter - University of Edinburgh - School of Biological Sciences

个人简介

After an undergraduate degree in Mathematics and a Ph.D. in Mathematical Physics with Andy Parry at Imperial College, I postdoc'd with Reinhard Lipowsky at the Max Planck Institute for Colloids and Interfaces, including a winter at Tel Aviv University with David Andelman, and then with Eric Siggia at the Rockefeller University. In 2002, I held my first faculty position at McGill University in the then Centre for Non-linear Dynamics under the wise mentorship of Leon Glass, Michael Guevara, and Mike Mackey. I returned to the UK, although as a joint Canadian citizen, in 2008 to become a SULSA Professor of Systems Biology at the University of Edinburgh.

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PS Swain, K Stevenson, A Leary, LF Montano-Gutierrez, IBN Clark, J Vogel, and T Pilizota (pdf, pubmed, software)Inferring time derivatives including growth rates using Gaussian processesNat Commun 7 (2016) 13766. K Stevenson, AF McVey, IBN Clark, PS Swain, and T Pilizota (pdf, pubmed)General calibration of microbial growth in microplate readersSci Rep 6 (2016) 38828. N Popovic, C Marr, and PS Swain (pdf, pubmed)A geometric analysis of fast-slow models for stochastic gene expression J Math Biol 72 (2016) 87. S Feng, JF Ollivier, PS Swain, and OS Soyer (pdf, SI, pubmed)BioJazz: in silico evolution of cellular networks with unbounded complexity using rule-based modelingNucleic Acids Res 43 (2015) e123. AY Weisse, DA Oyarzun, V Danos, and PS Swain (pdf, SI, pubmed, SBML/Matlab)Mechanistic links between cellular trade-offs, gene expression, and growthProc Nat Acad Sci USA 112 (2015) E1038. MM Crane, IBN Clark, E Bakker, S Smith, and PS Swain (pdf, SI, pubmed)A microfluidic system for studying ageing and dynamic single-cell responses in budding yeastPLoS One 9 (2014) e100042. CG Bowsher and PS Swain (pdf, pubmed)Environmental sensing, information transfer, and cellular decision-makingCurr Opin Biotechnol 28C (2014) 149. CA Lichten, R White, IBN Clark, and PS Swain (pdf, pubmed, software)Unmixing of fluorescence spectra to resolve quantitative time-series measurements of gene expression in plate readersBMC Biotechnol 14 (2014) 11. BMC Martins and PS Swain (pdf, SI, pubmed)Ultrasensitivity in phosphorylation-dephosphorylation cycles with little substratePLoS Comput Biol 9 (2013) e1003175. CG Bowsher, M Voliotis, and PS Swain (pdf, SI, pubmed)The fidelity of dynamic signaling by noisy biomolecular networks PLoS Comput Biol 9 (2013) e1002965. D Cottrell, PS Swain, and PF Tupper (pdf, SI, pubmed)Stochastic branching-diffusion models for gene expressionProc Nat Acad Sci USA 109 (2012) 9699. CG Bowsher and PS Swain (pdf, SI, summary, pubmed)Identifying sources of variation and the flow of information in biochemical networksProc Nat Acad Sci USA 109 (2012) E1320. JW Young, JC Locke, A Altinok, N Rosenfeld, T Bacarian, PS Swain, E Mjolsness, and MB Elowitz (pdf, pubmed)Measuring single-cell gene expression dynamics in bacteria using fluorescence time-lapse microscopyNat Protoc 7 (2011) 80. BMC Martins and PS Swain (pdf, pubmed)Trade-offs and constraints in allosteric sensingPLoS Comput Biol 7 (2011) e1002261. CA Lichten and PS Swain (pdf, pubmed, software)A Bayesian method for inferring quantitative information from FRET dataBMC Biophys 4 (2011) 10. JF Ollivier, V Shahrezaei, and PS Swain (pdf, SI, pubmed, software)Scalable rule-based modelling of allosteric proteins and biochemical networksPLoS Comput Biol 6 (2010) e1000975. MK Malleshaiah, V Shahrezaei, PS Swain, and SW Michnick (pdf, SI, pubmed)The scaffold protein Ste5 directly controls a switch-like mating decision in yeastNature 465 (2010) 101. TJ Perkins and PS Swain (pdf, pubmed)Strategies for cellular decision-makingMol Syst Biol 5 (2009) 326. F Siso-Nadal, JJ Fox, SA Laporte, TE Hebert, and PS Swain (pdf, pubmed)Signaling pathways can generate robust oscillations in calcium and cAMPPLoS One 4 (2009) e7189. V Shahrezaei and PS Swain (pdf, SI, pubmed, software)Analytical distributions for stochastic gene expressionProc Nat Acad Sci USA 105 (2008) 17256.Please note that Eqn. 13 should read F(z)= [f(z)]a = (1+b-bz)-a.