PILIZOTA, Teuta - University of Edinburgh - School of Biological Sciences

个人简介

2013 Chancellors Fellow 2008-2012 Postdoctoral research fellow, Princeton University 2007-2008 Postdoctoral researcher, University of Oxford, Department of Physics 2002-2007 Ph.D. in Biological Physics, University of Oxford, Department of Physics 1997-2002 Diploma in Physics, University of Zagreb, Faculty of Science, Department of Physics

研究领域

The lab focuses on developing novel tools for quantitative observations of changes in physiological parameters in single bacterial cells. By integrating state-of-the-art fluorescence imaging techniques, microfluidic devices, optical trapping techniques and microbiology methodologies, we are striving to understand the direct influence different stress response networks have on each other and on the survival of bacterial cells. We are particulalry interested in bacterial response to changes in external osmolarities and antibiotic treatment.

近期论文

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Pilizota T, Shaevitz JW. Origins of Escherichia coli growth rate and cell shape changes at high external osmolality. Biophys J October 2014, 107(8):1962-1969 Lo CJ, Sowa Y, Pilizota T, Berry RM. The mechanism and kinetics of a sodium-driven bacterial flagellar motor. PNAS 2013 Jul;110(28):E2544-51 doi: 10.1073/pnas.1301664110 Pilizota T, Shaevitz JW. Plasmolysis and cell shape depend on solute outer-membrane permeability during hyperosmotic shock in E. coli. Biophys J 18 June 2013, 104(12):2733-2742 Pilizota T, Shaevitz JW. Fast, Multiphase Volume Adaptation to Hyperosmotic Shock by Escherichia Coli. PlosOne 13 April 2012. 7(4):e35205 Fan B*, Branch RW*, Nicolau DV*, Pilizota T, Maini PK, Berry RM. Experimental evidence for stochastic allostery in the bacterial switch complex. Science.2010 Feb; 327(5966): 685-9. Pilizota T*, Brown M*, Leake MC, Branch RW, Berry RM, Armitage JP. A molecular brake, not a clutch, stops the Rhodobacter sphaeroides flagellar motor. PNAS. 2009 Jul;106(28):11582-7. Lo CJ, Leake MC, Pilizota T, Berry RM. Non-equivalence of membrane voltage and ion-gradient as driving forces for the bacterial flagellar motor at low load. Biophys J. 2007 Jul; 93(1):294-302 Pilizota T, Bilyard T, Bai F, Hosokawa H, Futai M, Berry RM. A programmable optical angle clamp for rotary molecular motors, Biophys J. 2007 Jul; 93(1):264-275