COLEGRAVE, Nick - University of Edinburgh - School of Biological Sciences

个人简介

1987-1990 Undergraduate, Biological sciences, Sussex University 1992-1995 PhD Sheffield University 1995-1996 NATO Fellow, McGill University 1997-1998 Postdoctoral researcher, St Andrews University 1999 Postdoctoral researcher, Glasgow University 2000 Zoology demonstrator, Edinburgh University 2000-2003 NERC research fellow, Edinburgh University 2003-2007 Lecturer in Biology 2008-Present Senior Lecturer in Biology

研究领域

My research interests are in the interface between ecology and evolution. Ecological interactions occur over a timescale of days or months, and have been viewed as essentially too quick to have relevance to long term evolution. Similarly, evolution was viewed as something that occurred over the millennia, and so of little importance to the day to day interactions studied by ecologists. However, it is slowly being realised that such a view is wrong and that the interaction between these fields is far more dynamic: The population dynamics of ecology will have profound effects on the selective forces of evolutionary biology which in turn will alter the properties of the organisms and affect their population dynamics. If we are to fully understand organic diversity, we need to consider both ecological and evolutionary forces, and the way in which they interact. Whilst my research has encompassed a wide range of organisms and specific questions, this general theme has run throughout. I do not limit myself to a single technique or study system, but instead attempt to use the best system for any particular question, often requiring a mixture of experimental and theoretical techniques. I am also actively involved in bringing evolutionary approaches to other field of biology, in particular infectious disease biology, and am part of several collaborative projects in this area

近期论文

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Lachapelle, J, Bell, GAC, and Colegrave, N (2015). Experimental adaptation to marine conditions by a freshwater alga. Evolution.69, 2662-2675. Ness, R. W. Morgan, A. D. Radhakrishnan, V. B. Colegrave, N and Keightley P. D. (2015) Extensive de novo mutation rate variation between individuals and across the genome of Chlamydomonas reinhardtii. Genome research. 25 doi:10.1101/gr.191494.115 Lagator, M. Morgan, A, Neve, P and Colegrave, N. (2014). The Role of sex and migration in adaptation to sink environments. Evolution 68, 2296, 2305. Little, T, J. , Allen J. E., Babayan, S.A. Matthews, K. R. and Colegrave, N (2012). Harnessing evolutionary biology to combat infectious disease. Nature Medicine. 18, 217 – 220. Hall, A and Colegrave, N. (2008) The decay of unused characters by selection and drift. Journal of Evolutionary Biology, 21, 610 – 617 Colegrave, N and Collins, S (2008) Experimental evolution and Evolvability. Heredity. doi: 10.1038/sj.hdy.6801095 Brockhurst MA, Colegrave N, Hodgson DJ and Buckling A (2007) Niche occupation limits adaptive radiation in experimental microcosms. PLoS ONE 2, e193 –e195 Hall, A & Colegrave, N. (2007). How does resource supply affect diversification? Proc. Roy. Soc. Lond. B. 274, 73 – 78. Nee, S., N. Colegrave, West, S. and Grafen, A. (2005). The illusion of invariant quantities in life histories Science, 309, 1236 – 1239 Colegrave, N. and Ruxton, G. D. (2003). Confidence intervals are a more useful compliment to non significant results than power analysis. Behavioural Ecology 14, 446-447. Buckling, A., M. A. Wills & N. Colegrave. (2003). Adaptation limits diversification in experimental bacterial populations. Science. 302, 2107 – 2109 Colegrave, N. (2002) Sex releases the speed limit on evolution. Nature 420, 664-666