CAI, Patrick - University of Edinburgh - School of Biological Sciences

个人简介

2010-2013 Postdoc training in Jef Boeke lab at Johns Hopkins University School of Medicine, USA 2007-2010 PhD in Genetics, Bioinformatics, and Computational Biology, Virginia Tech, USA 2005-2006 Master of Sciences in Informatics, University of Edinburgh, UK 2001-2005 Bachelor of Engineering with highest honor, Computer Sciences, Central South University, China

近期论文

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Leslie A. Mitchell*, Yizhi Cai*, Martin Taylor*, Anne Marie Noronha, James Chuang, Lixin Dai, and Jef D. Boeke. Multichange Isothermal Mutagenesis: a new strategy for multiple site-directed mutations in plasmid DNA. ACS Synth. Biol. 130311103855008 (2013). (*co-first authors, equal contribution) Wilson, Mandy*; Cai, Yizhi*; Hanlon, Regina; Taylor, Samantha; Chevreux, Bastien; Setubal, Jo?o; Tyler, Brett; Peccoud, Jean. (2012) Sequence-Verification of Synthetic DNA by Assembly of Sequencing Reads. Nucleic Acids Research. doi:10.1093/nar/gks908 (co-first author). Cai, Y. & Boeke, J. D (2011). Genome remodeling. Nature Biotechnology 29, 807–808. Cai, Y., Wilson, M., Peccoud, J. (2010) GenoCAD for iGEM: a grammatical approach to the design of standard-compliant constructs, Nucleic Acids Research, pp. gkq086v1. Cai, Y., Lux, M.W., Adam, L. and Peccoud, J. (2009) Modeling Structure-Function Relationships in Synthetic DNA Sequences using Attribute Grammars, PLoS Comput Biol, 5, e1000529. Czar, M.J., Cai, Y. and Peccoud, J. (2009) Writing DNA with GenoCAD, Nucleic Acids Res, 37, W40-47. Peccoud, J., Blauvelt, M.F., Cai, Y., Cooper, K.L., Crasta, O., DeLalla, E.C., Evans, C., Folkerts, O., Lyons, B.M., Mane, S.P., Shelton, R., Sweede, M.A. and Waldon, S.A. (2008) Targeted development of registries of biological parts, PLoS One, 3, e2671. Cai, Y., Hartnett, B., Gustafsson, C. and Peccoud, J. (2007) A syntactic model to design and verify synthetic genetic constructs derived from standard biological parts, Bioinformatics, 23, 2760-2767. Aleksic, J., F. Bizzari, Y.-Z. Cai, B. Davidson, K. de Mora, S. Ivakhno, S. Lalgudi Seshasayee, J. Nicholson, J. Wilson, A. El??ck, C. French, L. Kozma-Bognar, H.-W. Ma, and A. Millar. (2007) Development of a novel biosensor for the detection of arsenic in drinking water. IET Synthetic Biology 1:87-90.