个人简介
2016+ Lecturer in Bioinformatics, University of Edinburgh
2010-2015 Lecturer in Biology, University of St Andrews
2005-2010 Research Councils UK Academic Fellow in Evolutionary and Functional Genomics, University of St Andrews
2002-2005 Research Fellow, University of Reading
2001-2002 Developer, Ensembl project, Wellcome Trust Sanger Institute
1999-2001 Software Engineer and Software Engineer II, Analog Devices Inc
研究领域
Bioinformatics education, phylogeny reconstruction and philosophy of science.
4273π - Software for Teaching and Learning Computational Biology. http://4273pi.org
LVB - Reconstructing Evolution with Parsimony and Simulated Annealing. http://lvb.bio.ed.ac.uk
近期论文
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Darby C, Stolzer M, Ropp P, Barker D, Durand D (2017) Xenolog classification. Bioinformatics, 33, 640-649. http://dx.doi.org/10.1093/bioinformatics/btw686
Lim J-H, Latysheva NS, Iggo RD, Barker D (2016) Cluster analysis of p53 binding site sequences reveals subsets with different functions. Cancer Informatics, 15, 199-209. http://dx.doi.org/10.4137/CIN.S39968
Strobl MAR, Barker D (2016) On simulated annealing phase transitions in phylogeny reconstruction. Molecular Phylogenetics and Evolution, 101, 46-55. http://dx.doi.org/10.1016/j.ympev.2016.05.001
McDonagh JL, Barker D, Alderson RG (2016) Bringing computational science to the public. SpringerPlus, 5, 259. http://dx.doi.org/10.1186/s40064-016-1856-7
Barker D, Alderson RG, McDonagh JL, Plaisier H, Comrie MM, Duncan L, Muirhead GTP, Sweeney SD (2015) University-level practical activities in bioinformatics benefit voluntary groups of pupils in the last 2 years of school. International Journal of STEM Education, 2, 17. http://dx.doi.org/10.1186/s40594-015-0030-z
Wreggelsworth KM, Barker D (2015) A comparison of the protein-coding genomes of two green sulphur bacteria, Chlorobium tepidum TLS and Pelodictyon phaeoclathratiforme BU-1. BMC Research Notes, 8, 565. http://dx.doi.org/10.1186/s13104-015-1535-8
Robson JF, Barker D (2015) Comparison of the protein-coding gene content of Chlamydia trachomatis and Protochlamydia amoebophila using a Raspberry Pi computer. BMC Research Notes, 8, 561. http://dx.doi.org/10.1186/s13104-015-1476-2
Barker D (2015) Seeing the wood for the trees: philosophical aspects of classical, Bayesian and likelihood approaches in statistical inference and some implications for phylogenetic analysis. Biology & Philosophy, 30, 505-525. http://dx.doi.org/10.1007/s10539-014-9455-x
Alderson RG, Barker D, Mitchell JBO (2014) One origin for metallo-β-lactamase activity, or two? An investigation assessing a diverse set of reconstructed ancestral sequences based on a sample of phylogenetic trees. Journal of Molecular Evolution, 79, 117-129. http://dx.doi.org/10.1007/s00239-014-9639-7
Barker D, Ferrier DEK, Holland PWH, Mitchell JBO, Plaisier H, Ritchie MG, Smart SD (2013) 4273π: bioinformatics education on low cost ARM hardware. BMC Bioinformatics, 14, 243. http://dx.doi.org/10.1186/1471-2105-14-243
Lim J-H, Iggo RD, Barker D (2013) Models incorporating chromatin modification data identify functionally important p53 binding sites. Nucleic Acids Research, 41, 5582-5593. http://dx.doi.org/10.1093/nar/gkt260
Mendivil Ramos O, Barker D, Ferrier DEK (2012) Ghost loci imply Hox and ParaHox existence in the last common ancestor of animals. Current Biology, 22, 1951-1956. http://dx.doi.org/10.1016/j.cub.2012.08.023
Barker D (2012) A tribute to Peter Sneath. Taxon, 61, 481-483. http://www.ingentaconnect.com/content/iapt/tax/2012/00000061/00000002/art00033 [Corrigendum, Taxon, 61, 691. http://www.ingentaconnect.com/content/iapt/tax/2012/00000061/00000003/art00029 ]
Latysheva N, Junker VL, Palmer WJ, Codd GA, Barker D (2012) The evolution of nitrogen fixation in cyanobacteria. Bioinformatics, 28, 603-606. http://dx.doi.org/10.1093/bioinformatics/bts008
Brennan AC, Barker D, Hiscock SJ, Abbott RJ (2012) Molecular genetic and quantitative trait divergence associated with recent homoploid hybrid speciation: a study of Senecio squalidus (Asteraceae). Heredity, 108, 87-95. http://dx.doi.org/10.1038/hdy.2011.46
The Marie Curie SPECIATION Network (2012) What do we need to know about speciation? Trends in Ecology and Evolution, 27, 27-39. http://dx.doi.org/10.1016/j.tree.2011.09.002