Lipworth, Brian J - University of Dundee

个人简介

Initial BMedSCi at St Andrews, followed by MBChB with honours and MD at Manchester University, from 1986 registrar and senior registrar posts in Respiratory Medicine and Clinical Pharmacology in Dundee, followed by senior lecturer and professorial appointments. Awarded two prizes for research from the British Pharmacological Society, International Fellow of the American College of Allergy, Asthma and Immunology 2003 for contributions to airway allergy research, and International Visiting Professorship to Harvard Medical School in 2008.

研究领域

Current research interests are beta-adrenoceptor regulation and associated pharmacogenetics in asthma and COPD, airway inflammation in asthma, therapeutics of allergic rhinosinusitis

近期论文

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ANDERSON WJ, SHORT PM, WILLIAMSON PA, MORRISON AE, PALMER CAN, TAVENDALE R, LIPWORTH BJ. Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatics. Clin Sci 2014;126:75-83 (IF=4.859) SHORT PM, WILLIAMSON PA, ANDERSON WJ, LIPWORTH BJ. Randomised placebo controlled trial to evaluate chronic dosing effects of propranolol in asthma. Am J Respir Crit Care Med 2013;187:1308-1314 (IF=11.041) ANDERSON WJ, LIPWORTH BJ, REKHRAJ S, STRUTHERS A, GEORGE J. Left Ventricular Hypertrophy in Chronic Obstructive Pulmonary Disease without Hypoxaemia: The Elephant in the Room? Chest 2013;143:91-97(IF=5.854) MORALES DR, JACKSON C, LIPWORTH BJ, DONNAN PT, GUTHRIE B. Adverse respiratory effect of acute beta-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials. Chest 2013 doi:10.1378/chest.13-1235 (IF=5.854) SHORT PM, ANDERSON WJ, WILLIAMSON PA, LIPWORTH BJ. Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids. Heart 2013 doi:10.1136/heartjnl-2013-304769 (IF=5.014) LIPWORTH BJ, BASU K, DONALD HP, TAVENDALE R, MacGREGOR DF, OGSTON SA, PALMER CN, MUKHOPADHYAY S. Tailored second line therapy in asthmatic children with the arginine-16 genotype. Clin Sci 2013;124:521-528 (IF=4.859) ANDERSON W, McFARLANE L, LIPWORTH B. Prospective follow-up of novel markers of bone turnover in persistent asthmatics exposed to low and high doses of inhaled ciclesonide over 12 months. J Clin Endocrin Metab 2012;97:1929-1936 (IF=6.430) LIPWORTH BJ, SHORT PM, WILLIAMSON PA, CLEARIE KL, FARDON TC, JACKSON CM. A randomized primary care trial of Steroid Titration Against Mannitol IN persistent Asthma (STAMINA Trial). Chest 2012;141:607-615 (IF=5.854) ANDERSON WJ, SHORT PM, WILLIAMSON PA, LIPWORTH BJ. The FeNOtype Trial: Inhaled corticosteroid dose-response using domiciliary exhaled nitric oxide in persistent asthma. Chest 2012;142:1553-1561(IF=5.854) CLEARIE K, McKINLAY L, WILIAMSON P, LIPWORTH BJ. Fluticasone/Salmeterol combination confers benefits in smoking asthmatics. Chest 2012;141:330-338 (IF=5.854) SHORT P, WILLIAMSON P, ELDER D, LIPWORTH S, SCHEMBRI S, LIPWORTH B. The impact of tiotropium on mortality and exacerbations when added to inhaled corticosteroids and long acting beta-agonist therapy in COPD. Chest 2012;141:81-86 (IF=5.854)