Jovanovic, Aleksandar - University of Dundee

个人简介

Professor Jovanovic has obtained his MD/PhD degrees from the University of Belgrade. He has received his postdoctoral training at the Mayo Clinic where he was later appointed as Instructor of Medicine. In 1999 he joined the University of Dundee where he progressed through the ranks to Chair. Professor Jovanovic has published in many well-recognised peer-reviewed journals and his research was/is funded by mainstream funding bodies in UK and USA. He is a member of editorial boards of seven peer-reviewed journals and ad hoc referee for ~30 scientific journals and funding bodies.

近期论文

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Fernandes G, Dasai N, Kozlova N, Mojadidi A, Gall M, Drew E, Barratt E, Madamidola O, Brown S, Milne A, Martins Da Silva S, Whalley K, Barratt C, Jovanovic A. A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels. Hum. Reprod. 31: 287-297. Jovanovic S, Ballantyne T, Du Q, Blagojevic M, Jovanovic A. 2016. Phenylephrine preconditioning in embryonic heart H9c2 cells is mediated by up-regulation of SUR2B/Kir6.2: A first evidence for functional role of SUR2B in sarcolemmal KATP channels and cardioprotection. Int. J. Biochem. Cell. Biol. 70: 23-28. Mohammed Abdul KS, Jovanovic S, Du Q, Sukhodub A, Jovanovic A. 2015. A link between ATP and SUR2A: A novel mechanism explaining cardioprotection at high altitude. Int. J. Cardiol. 189: 73-76. Mohammed Abdul KS, Jovanovic S, Du Q, Sukhodub A, Jovanovic A. 2015. Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH. Biochim. Biophys. Acta-Mol. Basis. Dis.1852: 709-719. Mohammed Abdul KS, Jovanovic S, Du Q, Sukhodub A, Jovanovic A. 2014. Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen. Biochim. Biophys. Acta -Mol. Cell. Res. 1843: 2424-2431. Khan F, Choong WL, Du Q, Jovanovic A. 2013. Real time RT-PCR threshold cycles value for GAPDH from the blood correlate with measures of vascular endothelial function in humans. Clin. Transl. Sci. 6: 481-484. Jovanovic S, Khaja SMB, Jovanovic A. 2013. Cardioprotection afforded by SUR2A: An update. J. Cardiobiol. 1: 4.(review) Land S, Walker D, Du Q, Jovanovic A. 2013. Cardioprotective SUR2A promotes stem cell properties of cardiomyocytes. Int. J. Cardiol. 168: 5090-5092. Khan F, Choong WL, Du Q, Jovanovic A. 2013. Real time RT-PCR threshold cycles value for Kir6.1 from the blood correlate with parameters of vascular function: A potential for the vascular function biomarker? Biomarkers 18: 221-229 Du Q, Jovanovic S, Tulic L, Sljivancanin D, Jack DW, Zizic V, Khaja SMB, Tulic I, Jovanovic A. 2013. KATP channels are up-regulated with increasing age in human myometrium. Mech. Ageing Dev. 134: 98-102. Ballantyne T, Du Q, Jovanovic S, Neemo A, Holmes R, Sinha S, Jovanovic A. 2013. Testosterone protects female embryonic heart H9C2 cells against severe metabolic stress by activating estrogen receptors and up-regulating IES SUR2B. Int. J. Biochem. Cell. Biol. 45: 283-291. Beall C, Hamilton DL, Gallagher J, Logie L, Wright K, Soutar MP, Dadak S, Ashford FB, Haythorne E, Du Q, Jovanovic A, McCrimmon RJ, Ashford ML. 2012. Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour. Diabetologia 55: 2432-2444. (AJ advised design and execution of a part of the study part and a member of AJ laboratory has done a part of the experiments). Sukhodub A, Sudhir R, Du Q, Jovanovic S, Reyes S, Jovanovic A. 2011. Nicotinamide-rich diet improves physical endurance by upregulating SUR2A in the heart. J. Cell. Mol. Med. 15: 1703-1712. Sudhir R, Sukhodub A, Du Q, Jovanovic S, Jovanovic A. 2011. Ageing-induced decline in physical endurance in mice is associated with decrease in cardiac SUR2A and increase in cardiac susceptibility to metabolic stress: therapeutic Prospects for up-regulation of SUR2A. Biogerontology 12: 147-155. Du Q, Jovanovic S, Sukhodub A, Barratt E, Drew E, Whalley KM, Kay V, McLaughlin M, Telfer EE, Barratt CLR, Jovanovic A. 2010. Human oocytes express ATP-sensitive K+ channels. Hum. Reprod. 25: 2774-2782. Du Q, Jovanovic S, Sukhodub A, Jovanovic A. 2010. Infection with AV-SUR2A protects H9C2 cells against metabolic stress: a mechanism of SUR2A-mediated cytoprotection independent from the KATP channels activity. BBA-Mol. Cell. Res. 1803: 405-415. Sukhodub A, Du Q, Jovanovic S, Jovanovic A. 2010. Nicotinamide-rich diet protects the heart against ischaemia-reperfusion in mice: a crucial role for cardiac SUR2A. Pharmacol. Res. 61: 564-570. Rafiqi FH, Zuber AM, Glover M, Richardson C, Fleming S, Jovanovic S, Jovanovic A, O’Shaughnessy KM, Alessi DR. 2010. Role of the WNK-activated SPAK kinase in regulating blood pressure. EMBO Mol. Med. 2: 63-75. Jovanovic S, Du Q, Sukhodub A, Jovanovic A. 2009. M-LDH physically associated with sarcolemmal KATP channels mediates cytoprotection in heart embryonic H9C2 cells. Int. J. Biochem. Cell. Biol., 41: 2295-2301. Jovanovic S, Du Q, Sukhodub A, Jovanovic A. 2009. Dual mechanism of cytoprotection afforded by M-LDH in embryonic heart H9C2 cells. BBA-Mol. Cell. Res.,1793: 1379-1386. Jovanovic S, Du Q, Mukhopadhyay S, Swingler R, Buckley R, McEachan J, Jovanovic A. 2008. A patient suffering from hypokalemic periodic paralysisis is deficient in skeletal muscle ATP-sensitive K+ channels. Clin. Transl. Sci. 1: 71-74. Sukhodub A, Jovanovic S, Du Q, Budas GR, Clelland A, Shen M, Sakamoto K, Tian R, Jovanovic A. 2007. AMP-activated protein kinase mediates preconditioning in cardiomyocytes by regulating activity and trafficking of sarcolemmal ATP-sensitive K+ channels. J. Cell. Physiol., 210: 224-236.