个人简介
Masaru Nakamoto received his M.D. at Kobe University School of Medicine, Japan, in 1986. After finishing his residency in internal medicine, he completed his Ph.D. in biochemistry and molecular biology at Kagoshima University, Japan, in 1993. He then worked as a post-doctoral fellow in Dr. John Flanagan's laboratory at Harvard Medical School in the USA (1993-1998). From 1999 to 2006, he was an Assistant Professor/Staff at the Lerner Research Institute of the Cleveland Clinic Foundation and at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, in the USA. In 2006, he was appointed a Senior Lecturer at the University of Aberdeen
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Nakamura, R., Oyama, T., Tajiri, R., Mizokami, A., Namiki, M., Nakamoto, M. & Ooi, A. (2015). 'Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma'. Cancer Science, vol 106, no. 5, pp. 656-664. DOI: [ONLINE] DOI: 10.1111/CAS.12649 [ONLINE] AURA: NAKAMURA_ET_AL_2015_CANCER_SCIENCE.PDF
Nakamoto, C., Kuan, SL., Findlay, AS., Durward, E., Ouyang, Z., Zakrzewska, E., Endo, T. & Nakamoto, M. (2014). 'Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development'. Molecular Biology of the Cell, vol 25, no. 2, pp. 234-244. DOI: [ONLINE] DOI: 10.1091/MBC.E13-08-0453 [ONLINE] AURA: MBC2014.PDF
Nakamura, R., Nakamoto, C., Obama, H., Durward, E. & Nakamoto, M. (2012). 'Structure-function analysis of Nel, a thrombospondin-1-like glycoprotein involved in neural development and functions'. The Journal of Biological Chemistry, vol 287, no. 5, pp. 3282-3291. DOI: [ONLINE] DOI: 10.1074/JBC.M111.281485
Jiang, Y., Obama, H., Kuan, SL., Nakamura, R., Nakamoto, C., Ouyang, Z. & Nakamoto, M. (2009). 'In vitro guidance of retinal axons by a tectal lamina-specific glycoprotein Nel'. Molecular and Cellular Neuroscience, vol 41, no. 2, pp. 113-119. DOI: [ONLINE] DOI: 10.1016/J.MCN.2009.02.006
Bjartmar, L., Huberman, AD., Ullian, EM., Renteria, RC., Liu, X., Xu, W., Prezioso, J., Susman, MW., Stellwagen, D., Stokes, CC., Cho, R., Worley, P., Malenka, RC., Ball, S., Peachey, NS., Copenhagen, D., Chapman, B., Nakamoto, M., Barres, BA. & Perin, MS. (2006). 'Neuronal pentraxins mediate synaptic refinement in the developing visual system'. Journal of Neuroscience, vol 26, no. 23, pp. 6269-6281. DOI: [ONLINE] DOI: 10.1523/JNEUROSCI.4212-05.2006 [ONLINE] AURA: J_NEUROSCI_26_6269.PDF
Matsuoka, H., Obama, H., Kelly, ML., Matsui, T. & Nakamoto, M. (2005). 'Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration'. The Journal of Biological Chemistry, vol 280, no. 32, pp. 29355-29363. DOI: [ONLINE] DOI: 10.1074/JBC.M500010200
Feldheim, DA., Nakamoto, M., Osterfield, M., Gale, NW., DeChiara, TM., Rohatgi, R., Yancopoulos, GD. & Flanagan, JG. (2004). 'Loss-of-function analysis of EphA receptors in retinotectal mapping'. Journal of Neuroscience, vol 24, no. 10, pp. 2542-2550. DOI: [ONLINE] DOI: 10.1523/JNEUROSCI.0239-03.2004 [ONLINE] AURA: JN_2004.PDF
Nishida, K., Flanagan, JG. & Nakamoto, M. (2002). 'Domain-specific olivocerebellar projection regulated by the EphA-ephrin-A interaction'. Development, vol 129, no. 24, pp. 5647-5658. DOI: [ONLINE] DOI: 10.1242/DEV.00162
Nakamoto, M., Cheng, H-J, Friedman, GC., McLaughlin, T., Hansen, MJ., Yoon, CH., O'Leary, DDM. & Flanagan, JG. (1996). 'Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo'. Cell, vol 86, no. 5, pp. 755-766. DOI: [ONLINE] DOI: 10.1016/S0092-8674(00)80150-6 [ONLINE] AURA: CELL_1996.PDF
Cheng, H-J, Nakamoto, M., Bergemann, AD. & Flanagan, JG. (1995). 'Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map'. Cell, vol 82, pp. 371-381. [ONLINE] AURA: CELL_1995.PDF