Galley, Helen - University of Aberdeen - School of Medicine, Medical Sciences and Nutrition

个人简介

Helen Galley obtained her PhD in human zinc metabolism from the University of Leeds in 1989. She developed an interest in free radicals and antioxidants and later became involved in intensive care and liver transplantation research. Professor Galley was appointed to the post of Lecturer in Anaesthesia & Intensive Care in Aberdeen in 1995 and was promoted to Senior Lecturer in 2002 and awarded a Personal Chair in 2010. Professor Galley has published on a wide range of topics and her research interests now focus on modulation of inflammatory and immune responses in the critically ill, particularly the role of mitochondria targeted antioxidants in sepsis. She was awarded the Sir Humprey Davy medal by the Royal College of Anaesthetists in 2002, for her services to Anaesthesia Research in the UK and in 2011 was awarded a Fellowship of the Royal College of Anaesthetists. In 2012 she was also awarded Fellowship of the Royal Society of Biology by election and an honorary Fellowship of the Faculty of Intensive Care Medicine in 2016.

研究领域

Mechanisms of the inflammatory and immune responses in the critically ill and their modulation as potential therapeutic approaches.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Lowes, DA., Galley, HF., Moura, APS. & Webster, NR. (2017). 'Brief isoflurane anaesthesia affects differential gene expression, gene ontology and gene networks in rat brain'. Behavioural Brain Research, vol 317, pp. 453-460. DOI: [ONLINE] DOI: 10.1016/J.BBR.2016.09.045 McCormick, B., Lowes, DA., Colvin, L., Torsney, C. & Galley, HF. (2016). 'MitoVitE, a mitochondria-targeted antioxidant, limits paclitaxel-induced oxidative stress and mitochondrial damage in vitro, and paclitaxel-induced mechanical hypersensitivity in a rat pain model'. British Journal of Anaesthesia, vol 117, no. 5, pp. 659-666. DOI: [ONLINE] DOI: 10.1093/BJA/AEW309 McCreath, G., Scullion, MMF., Lowes, DA., Webster, NR. & Galley, HF. (2016). 'Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis'. British Journal of Anaesthesia, vol 116, no. 1, 26675956, pp. 131-139. [ONLINE] AURA: GALLEY_SIRTUIN_PAPER_BJA_FINAL_ACCEPTED_VERSION_FOR_PURE.PDF Mertens, K., Lowes, DA., Webster, NR., Talib, J., Hall, L., Davies, MJ., Beattie, JH. & Galley, HF. (2015). 'Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation'. British Journal of Anaesthesia, vol 114, no. 6, pp. 990-999. DOI:[ONLINE] DOI: 10.1093/BJA/AEV073 Galley, HF., Lowes, DA., Thompson, K., Wilson, ND., Wallace, CA. & Webster, NR. (2015). 'Characterisation of gamma delta (γδ) T cell populations in patients with sepsis'. Cell Biology International, vol 39, no. 2, pp. 210-216. DOI: [ONLINE] DOI: 10.1002/CBIN.10361 Galley, HF., Lowes, DA., Allen, L., Cameron, G., Aucott, LS. & Webster, NR. (2014). 'Melatonin as a potential therapy for sepsis: a phase I dose escalation study and an ex vivo whole blood model under conditions of sepsis'. Journal of Pineal Research, vol 56, no. 4, pp. 427-438. DOI: [ONLINE] DOI: 10.1111/JPI.12134 [ONLINE] AURA: DAMSEL_STUDY.PDF Galley, HF. & Colvin, LA. (2013). 'Next on the agenda: Gender'. British Journal of Anaesthesia, vol 111, no. 2, pp. 139-142. DOI: [ONLINE] DOI: 10.1093/BJA/AET133 Lowes, DA., Webster, NR., Murphy, MP. & Galley, HF. (2013). 'Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis'. British Journal of Anaesthesia, vol 110, no. 3, pp. 472-480. DOI: [ONLINE] DOI: 10.1093/BJA/AES577 Lowes, DA., Almawash, AM., Webster, NR., Reid, VL. & Galley, HF. (2011). 'Melatonin and structurally similar compounds have differing effects on inflammation and mitochondrial function in endothelial cells under conditions mimicking sepsis'. British Journal of Anaesthesia, vol 107, no. 2, pp. 193-201. DOI: [ONLINE] DOI: 10.1093/BJA/AER149 Lowes, DA. & Galley, HF. (2011). 'Mitochondrial protection by the thioredoxin-2 and glutathione systems in an in vitro endothelial model of sepsis'. Biochemical Journal, vol 436, no. 1, pp. 123-132. DOI: [ONLINE] DOI: 10.1042/BJ20102135 [LINK] HTTP://WWW.BIOCHEMJ.ORG/BJ/436/0123/4360123.PDF