Presneau, Nadege - University of Westminster - Department of Biomedical Sciences

个人简介

I obtained an equivalent of BSc (D.E.U.G and Licence) in France in Cell Biology and Physiology from University Blaise Pascal in France (Clermont II, Faculty of Sciences and Technologies). I continued my postgraduate studies with a master in Molecular Biology and Immunology Applied and a PhD in Molecular Biology in the Laboratory of Molecular Oncology led by Prof Yves-Jean Bignon (Thesis title: Search for new onco-suppressor genes implicated in hereditary predisposition to breast cancer ; University Blaise Pascal). I continued my interest in Cancer Genetics with my first postdoctoral position in Montreal (Quebec - Canada) in the department of Human Genetics at McGill University in the lab of Dr Patricia Tonin. During four years I was investigating a putative tumour suppressor region on Chromosome 17q25 in somatic ovarian cancer. I became familiar with high throughput technologies such as gene expression microarrays (GEM, Genechips from Affymetrix ) to identify new tumour suppressor genes involved in sporadic ovarian cancer. After this first position, I moved to London in Prof Chris Boshoff lab (18 months) and in Prof Adrienne Flanagan’s lab (9 years) at UCL where I continued my interest in cancer genetics and genomics but this time on mesenchymal (sarcoma) and bone neoplasms. I joined recently the University of Westminster in May 2014. I am the Designated Individual on the Human Tissue Authority research Licence (12015). I am a member of the editorial board of Pathogenesis a RCPath Journal (Royal College of Pathologists) I am co-editor of a new text book title provisionally entitled 'Molecular Diagnostics' for Oxford University Press (OUP) in the Biomedical Sciences series scheduled to be published by end of 2017. I obtained a Postgraduate Certificate (PG Cert) in Higher Education in March 2016 and I am a Fellow of the Higher Education Academy (FHEA). Since October 2016 I am the Director of the 'Westminster Genomics Services' (wgs@westminster.ac.uk).

研究领域

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My research focuses principally on developing new bioinformatics approaches in collaboration with the department of computer science (Dr Aleka Psarrou and Mr Markos Mentzelopoulos) and UCL (Division of Surgery & Interventional Science - Dr Rifat Hamoudi) to identify driver gene(s) involved in breast cancer (BC) using high throughput technologies such as Next Generation Sequencing (NGS). I am also interested in the development of new diagnostic tool for cancer as well as biobanking and ethics in translational research.