Curley, Paul - University of Westminster - Department of Life Sciences

个人简介

I read for a BSc degree (1985) and a PhD (1989) degree in Biochemistry at University College Dublin (UCD) under Prof. Stephen Mayhew investigating structure-function relationships in flavodoxins (small flavoproteins involved in a number of low potential oxidation-reduction reactions such as nitrogen fixation, sulphate reduction, etc.) before working with Dr John Dalton at Dublin City University looking at how malarial parasites bind to red blood cells. Following this work, I moved onto the University of Manchester to work on a Sanofi-Aventis funded project developing small molecule inhibitors of integrins (proteins that play an essential function in cell adhesion) in Prof. Martin Humphries' laboratory before being appointed Lecturer in Biochemistry at the University of Westminster in 2000. In addition, I have also worked for periods at both the University of Calgary and at the University of Notre Dame.

研究领域

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Current research interests include: computational methods for protein structure prediction; in silico molecular modelling of ligand binding; lectin-carbohydrate interactions; autophagy in Trichomonas vaginalis; role of melanocortin peptides in osteoarthritis.