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研究领域

Metallo-organic chemistry, particularly the design of self-assembling chiral systems; their applications as medicines for challenging diseases (superbugs, cancer), catalysts for enantioselective transformations of organic molecules, and polyolefin materials for industry

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Metallohelices: potential mimetics of alpha-helical peptides in cancer treatment? R. A. Kaner and P. Scott, Future Med. Chem., 2015 Asymmetric triplex metallohelices with high and selective activity against cancer cells Alan D. Faulkner, Rebecca A. Kaner, Qasem M. A. Abdallah, Guy Clarkson, David J. Fox, Pratik Gurnani, Suzanne E. Howson, Roger M. Phillips, David I. Roper, Daniel H. Simpson, Peter Scott, Nature Chem. 2014 Chiral Metallohelical Complexes Enantioselectively Target Amyloid β for Treating Alzheimer’s Disease Meng Li, Suzanne E. Howson, Kai Dong, Nan Gao, Jinsong Ren, Peter Scott, Xiaogang Qu, J. Am. Chem. Soc. 2014 Metallohelices with Activity Against Cisplatin-Resistant Cancer Cells; does the mechanism involve DNA binding? Viktor Brabec, Suzanne E. Howson, Rebecca A Kaner, Rianne M. Lord, Jaroslav Malina, Roger M Phillips, Qasem MA Abdallah, Patrick C. McGowan, Alison Rodger, Peter Scott, Chem. Sci. 2013 Optically pure, water-stable metallo-helical ‘flexicate’ assemblies with antibiotic activity Suzanne E. Howson, Albert Bolhuis, Viktor Brabec, Guy J. Clarkson, Jaroslav Malina, Alison Rodger, Peter Scott, Nature Chem. 2012, 4, 31-36. Isomeric Fe(II) MOFs: from a diamond-framework spin-crossover material to a 2D hard magnet Lihong Li, Guy J. Clarkson, David J. Evans, Martin R. Lees, Scott S. Turner and Peter Scott, Chem.Comm., 2011, 47, 12646 - 12648. Structural and Electronic Modulation of Magnetic Properties in a Family of Chiral Iron Coordination Polymers Lihong Li, Jan M. Becker, Laura E. N. Allan, Guy J. Clarkson, Scott S. Turner, and Peter Scott, Inorg. Chem. 2011, 50, 5925–5935.

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