研究领域
New methods of polymer synthesis and catalysis. Specific interests include controlled polymerisation of acrylics and esters by organometallic initiators and catalysts, e.g. atom transfer living polymerisation, catalytic chain transfer polymerisation. Mechanisms of polymerisation and utilisation of this knowledge to design catalysts and organic polymers for specific commercial applications. Environmentally friendly polymerisation and use of biomimetic chemistry in this area.
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Tunable thermo-responsive polymer-protein conjugates via a combination of nucleophilic thiol-ene "click" and SET-LRP Jones Mathew W.; Gibson Matthew I.; Mantovani Giuseppe; Haddleton David M. POLYMER CHEMISTRY 2011, 2, 572-574, DOI: 10.1039/c0py00329h
Synthesis and modification of thermoresponsive poly(oligo(ethylene glycol) methacrylate) via catalytic chain transfer polymerization and thiol-ene Michael addition Soeriyadi Alexander H.; Li Guang-Zhao; Slavin Stacy; Haddleton David M. et al. POLYMER CHEMISTRY 2011, 2, 815-822 DOI: 10.1039/c0py00372g
Glycopolymers via catalytic chain transfer polymerisation (CCTP), Huisgens cycloaddition and thiol-ene double click reactions L. Nurmi, J. Lindqvist, R. Randev, J. Syrett and D. M. Haddleton, Chemical Communications, 2009, 19, 2727-2729
Advances in PEGylation of important biotech molecules: delivery aspects S. M. Ryan, G. Mantovani, X. X. Wang, Haddleton, D. M. And D. J. Brayden, Expert Opinion on Drug Delivery, 2008, 5, 371-383
High-Affinity Glycopolymer Binding to Human DC-SIGN and Disruption of DC-SIGN Interactions with HIV Envelope Glycoprotein Becer C. Remzi; Gibson Matthew I.; Geng Jin; Haddleton, David M. et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2010, 132, 15130-15132, DOI: 10.1021/ja1056714