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个人简介

Professor Skene is Section Head of Chronobiology. She has over 25 years of research experience studying the human circadian timing system and has authored over 150 refereed research publications. Her recent research has been funded by the EU FP6 and FP7 programmes, UK Cross Research Council New Dynamics of Ageing (NDA) Programme, the BBSRC (UK) and Philips Lighting. She is currently a Royal Society Wolfson Research Merit Award Holder. Professor Skene is currently President of the European Biological Rhythms Society (EBRS) (2012- ) (Secretary-Treasurer2002-2009; Vice-President 2012-2015) and is a past Vice-President (Basic) of the European Sleep Research Society (ESRS) (2010-2014). In 2009 Prof Skene established the Joint ESRS-EBRS Symposia that take place each year at the biennial ESRS and EBRS Congresses. She is a past Chair of a Gordon Research Conference (Pineal Cell Biology, 2012), currently an Associate Editor of the Journal of Sleep Research and on the Editorial Board of Chronobiology International. She is a Co-Director of Stockgrand Ltd and Surrey Assays Ltd, University-based companies specialising in the measurement of melatonin and other circadian rhythm markers.

研究领域

Circadian rhythms in the blind, effect of visual loss and visual pathologies Characterisation and treatment of circadian rhythm disorders as experienced by blind people, shift workers, transmeridian air travellers and older people Role of endogenous and exogenous melatonin in circadian rhythm sleep disorders Investigation of circadian photoentrainment (optimum characteristics of light and melatonin) in humans Non visual light responses and characteristics of the circadian photoreception pathway in humans; age-related changes in the circadian timing system; effect of light on sleep, activity and the clock Human circadian rhythms, sleep and metabolism in health, circadian disorders and metabolic diseases (shift workers, Type 2 diabetes, liver disease).

近期论文

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Giskeodegard GF, Davies SK, Revell VL, Keun H, Skene DJ. (2015) 'Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation'. NATURE PUBLISHING GROUP SCIENTIFIC REPORTS, 5 Article number ARTN 14843 doi: 10.1038/srep14843 Moreno CRC, Vasconcelos S, Marqueze EC, Lowden A, Middleton B, Fischer M, Louzada FM, Skene DJ. (2015) 'Sleep patterns in Amazon rubber tappers with and without electric light at home'. NATURE PUBLISHING GROUP SCIENTIFIC REPORTS, 5 Article number ARTN 14074 doi: 10.1038/srep14074 Davies SK, Ang JE, Revell VL, Holmes B, Mann A, Robertson FP, Cui N, Middleton B, Ackermann K, Kayser M, Thumser AE, Raynaud FI, Skene DJ. (2014) 'Effect of sleep deprivation on the human metabolome'. NATL ACAD SCIENCES PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111 (29), pp. 10761-10766. doi: 10.1073/pnas.1402663111 Lucas RJ, Brown TM, Peirson SN, Berson DM, Cooper HM, Czeisler CA, Lockley SW, Figueiro MG, Gamlin PD, O'Hagan JB, Price LLA, Provencio I, Skene DJ, Brainard GC. (2014) 'Measuring and using light in the melanopsin age'. Trends in Neurosciences, 37 (1), pp. 1-9. doi: 10.1016/j.tins.2013.10.004

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