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个人简介

Professor Margaret Rayman has a doctorate in Inorganic Biochemistry from Somerville College, Oxford, and has held post-doctoral fellowships at the Institute of Cancer Research and Imperial College. Since 2007, she has been Professor of Nutritional Medicine at the University of Surrey where, in 1998, she set up, and now directs, the highly respected MSc Programme in Nutritional Medicine. In 2014, she was appointed Visiting Professor at the First Affiliated Hospital Xi’an Jiaotong University School of Medicine, Xi’an, China. Her research, which includes a number of randomised controlled trials, centres on the importance of trace elements to human health with particular emphasis on selenium and iodine in populations with marginal selenium or iodine deficiency. She has published widely on the effects of selenium on human health including a number of highly cited reviews in The Lancet. As part of her extensive work on iodine, her group found a significant association between mild-to-moderate iodine deficiency in UK pregnant women of the ALSPAC cohort and poorer IQ and reading ability in the offspring at ages 8 and 9 (Lancet 2013).

研究领域

Since returning from a lengthy career gap (20-years out of research), my work, has focused on trace elements of importance to health, most notably selenium and iodine (see selected publications below). I am interested in: the effect of low selenium status on - the risk of hypertensive conditions of pregnancy, most notably pre-eclampsia; - thyroid function and auto-immune thyroid disease; - the risk of type-2 diabetes; - plasma lipids the effect of iodine status in pregnancy on cognitive, auditory and psychomotor development in the child and on pregnancy outcome.

近期论文

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Bath SC, Pop VJM, Furmidge-Owen VL, Broeren MAC, Rayman MP. (2016) 'Thyroglobulin as a functional biomarker of iodine status in a cohort study of pregnant women in the United Kingdom'. Thyroid, doi: 10.1089/thy.2016.0322 Gladyshev VN, Arnér ES, Berry MJ, Brigelius-Flohé R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Flohé L, Green FR, Guigó R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, Köhrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Prabhu KS, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonović M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y. (2016) 'Selenoprotein Gene Nomenclature'. Journal of Biological Chemistry, doi: 10.1074/jbc.M116.756155 Bath SC, Rayman MP. (2016) 'Trace element concentration in organic and conventional milk: what are the nutritional implications of the recently reported differences?'. CAMBRIDGE UNIV PRESS BRITISH JOURNAL OF NUTRITION, 116 (1), pp. 3-6. doi: 10.1017/S0007114516001616

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