Bodman-Smith, Kikki - University of Surrey - School of Biosciences and Medicine

个人简介

BSc Biology, Royal Holloway and Bedford New College, University of London PhD Immunology, University College London, University of London

研究领域

Current research interests lie in understanding the role of the inflammatory acute phase proteins in innate immune responses to infection and in inflammatory disease and how they may interact with the acquired immune response. This can be further divided into (i) The effect of acute phase proteins on host cells particularly in relation to inflammatory disease (ii) Host cell receptors used by acute phase proteins for pathogen uptake and (iii) The role of acute phase proteins on pathogen survival.

近期论文

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Shams, S., Shafi, S., Bodman-Smith, K., Williams, P., Mehta, S. and Ferns, G. 2008. Anti-heat shock protein-27 (Hsp-27) antibody levels in patients with chest pain: Association with established cardiovascular risk factors. Clin. Chim. Acta. 395: 42-46. Casey, R., Newcombe, J., McFadden, J. and Bodman-Smith, K.B. 2008. The acute phase reactant C-reactive protein binds to phosphorylcholine-expressing Neisseria meningitidis and increases uptake by human phagocytes. Infect. Immun; 76(3): 1298-1304. Karam, M. C., Hamdan, H. G., Abi Chedid, N. A., Bodman-Smith, K. B. and Baroody, G. M. 2007. Interleukin-10 reduces hyperalgesia and the level of interleukin-1b in BALB/c mice infected with Leishmania major with no major effect on the level of interleukin-6. J. Neuroimmunol; 183(1-2): 43-49. Karam, M., Bodman-Smith, K. B., Eales-Reynolds, L-J. and Baroody, G. 2006. Low Dose of Leishmania major causes hyperalgesia in mice during early infection accompanied by the upregulation of interleukin-1 beta and interleukin-6. Exp. Parasitol; 113: 168-173. Eales-Reynolds, L-J. and Bodman-Smith, K. 2005. Blended Learning: Investigation of its Effectiveness at encouraging deeper learning in an introductory science course. Innovation and Development in Learning Teaching and Support: New and different ways in supporting teaching and learning. ISBN: 1-86137-425-9. 51-57. Rodriguez, J. A., Bodman-Smith, K. B. and Raynes, J. G. 2004. Neutrophil responses to C-reactive protein are not dependent on polymorphism R/H131 of human FcRIIa. Clin. Exp. Immmunol; 138: 271-277. Bodman-Smith, K. B., Gregory, R., Harrison, P. T. and Raynes J. G. 2004. FcRIIa expression with FcRI results in C-reactive protein- and IgG-mediated phagocytosis. J. Leukocyte Biol. 75: 1029-1035. Bodman-Smith, K. B., Mbuchi, M., Culley, F. J., Bates, P. A. and Raynes, J. R. 2002. C-reactive protein mediated phagocytosis of Leishmania donovani promastigotes does not alter parasite survival or macrophage responses. Parasite Immunnol; 24; 447-454. Bodman-Smith, K. B., Melendez, A., Campbell, I., Harrison, P., Allen, J. A. and Raynes, J. G. 2002. C-reactive protein mediated phagocytosis and phospholipase D signalling through the high affinity receptor for IgG (FcRI). Immunol; 107: 252-260.