Avignone Rossa, Claudio - University of Surrey - School of Biosciences and Medicine

个人简介

Claudio obtained his degree in Chemistry (1987), followed by a Licentiate degree in Biochemical Sciences (1989) and a PhD in Biochemical Sciences (1994) from the University of La Plata (Argentina). He was appointed Associate Professor of Biotechnology at the University of Quilmes (Argentina) in 1994, and moved to the University of Amsterdam, where he joined the Microbial Physiology Group as a Research Fellow from 1995 to 1999. He joined the University of Surrey as a Research Associate in 1999, and was appointed as Lecturer in Microbial Physiology in 2000, promoted to Senior Lecturer in Microbial Systems Biology in 2006 and became a Reader in 2012.

研究领域

My research interests are in the field of Quantitative Microbial Physiology, Metabolic Modelling and Metabolic Engineering. In silico analysis of metabolic networks for the prediction of metabolic capabilities Metabolic modelling and quantitative physiology of microorganisms for the production of bioactive molecules Metabolic Engineering of microorganisms (e.g. Streptomyces, yeasts) for the improvement of biosynthetic activities. Our goal is the rational improvement of the capability of microorganisms for the production of compounds of medical and industrial interest.

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Ahmed AESI, Wardell JN, Thumser AE, Avignone-Rossa CA, Cavalli G, Hay JN, Bushell ME. (2011) Metabolomic Profiling Can Differentiate Between Bactericidal Effects of Free and Polymer Bound Halogen. J Appl Polym Sci, 119, 709 – 718. Efthimiou G, Thumser AE, Avignone Rossa CA (2008). A novel finding that Streptomyces clavuligerus can produce the antibiotic clavulanic acid using olive oil as a sole carbon source. J Appl Microbiol, 105, 2058-2064. (doi:10.1111/j.1365-2672.2008.03975.x). Download Beste DJV, Laing E, Bonde B, Avignone-Rossa C, Bushell ME, and McFadden JJ (2007) Transcriptomic analysis identifies growth rate modulation as a component of the adaptation of mycobacteria to survival inside the macrophage. J Bacteriol 189, 3969 – 3976 Rozkov A, Avignone-Rossa CA, Ertl PF, Jones P, O’Kennedy RD, Smith JJ, Dale JW, Bushell ME (2005). Fed batch culture with declining specific growth rate for high-yielding production of a plasmid containing a gene therapy sequence in Escherichia coli DH1. Enz Microbial Technol 39, 47-50 Beste DJV, Peters J, Hooper T, Avignone-Rossa C, Bushell ME, McFadden J (2005) Compiling a Molecular Inventory for Mycobacterium bovis BCG at Two Growth Rates: Evidence for Growth Rate-Mediated Regulation of Ribosome Biosynthesis and Lipid Metabolism. J Bacteriol 187, 1677 – 1684 Rozkov A, Avignone-Rossa CA, Ertl PF, Jones P, O’Kennedy RD, Smith JJ, Dale JW, Bushell ME (2004). Characterization of the metabolic burden on Escherichia coli DH1 cells imposed by the presence of a plasmid containing a gene therapy sequence. Biotechnol Bioeng 88, 910-915