Ahmadi, Kourosh - University of Surrey - School of Biosciences and Medicine

个人简介

I graduated with an honours degree in Biochemistry from Imperial College, followed by an MSc in Epidemiology & Public Health from London School of Hygiene & Tropical Medicine, and a PhD in population genetics from King's College London (2002). My professional employment started with post-doctoral training at University College London, followed by academic positions, first as a fellow and then as a senior lecturer at Kings College London. I started my employment as a Reader in Nutritional Genomics at the university of Surrey in November 2012.

研究领域

My research focuses on the molecular characterisation of the causes, characteristics and consequences of variable disposition and response to B-vitamins and 1-Carbon Metabolism with the over-arching goal of improving primary and secondary prevention and risk-management strategies for common ageing diseases, most notably age-associated cognitive decline and dementia.

近期论文

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Cotlarciuc I, Malik R, Holliday EG, Ahmadi KR, et al. Effect of genetic variants associated with plasma homocysteine levels on stroke risk. Stroke. 2014 Jul;45(7):1920-4; Ahmadi KR, Andrew T. Opportunism: a panacea for implementation of whole-genome sequencing studies in nutrigenomics research? Genes Nutr. 2014 Mar;9(2):387; Bell JT, Loomis AK, Butcher LM, Gao F, et al. Differential methylation of the TRPA1 promoter in pain sensitivity. Nat Commun. 2014;5:2978; Andrew T, Gill R, Gillham-Nasenya I, Ahmadi KR. Unravelling the basis of variability in cobalamin levels in the general population. Br J Nutr. 2013 Nov 14;110(9):1672-9; Grundberg E, Meduri E, Sandling JK, Hedman AK, et al. Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. Am J Hum Genet. 2013 Nov 7;93(5):876-90; van Meurs JB, Pare G, Schwartz SM, Hazra A, et al & Ahmadi KR. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr. 2013 Sep;98(3):668-76; Rahmioglu N, Heaton J, Clement G, Gill R, Surdulescu G, Zlobecka K, Hodgkiss D, Smith NW, Ahmadi KR. Genome-wide association study reveals a complex genetic architecture underpinning-induced CYP3A4 enzyme activity. Eur J Drug Metab Pharmacokinet. 2013 Mar;38(1):63-7; MuTHER consortium. Mapping cis and trans regulatory variants across multiple tissues in twins. Nat Genet. 2012 Sep 2; Manning AK, Hivert MF, et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet. 2012 May 13;44(6):659-69. Bell JT, Tsai PC, Yang TP, Pidsley R, et al. Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet. 2012 Apr;8(4):e1002629.