Willett, Mark - University of Southampton - Discipline of Biological Sciences

个人简介

Career history 2013-present: Imaging Service Manager. University of Southampton, UK. PostDoctural Research Fellow. University of Sussex, UK. Academic qualifications 2006: DPhil Biochemistry. University of Sussex, UK. 2002: BSc Cellular and Molecular Biology. University of Kent, UK.

研究领域

My work has focused on using advanced microscopy to investigate the role of localised protein synthesis in regulating cytoskeleton reorganisation in migrating mesenchymal cells.

近期论文

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mTOR kinase-dependent, but raptor-independent regulation of downstream signaling is important for cell cycle exit and myogenic differentiation - Pollard, H.J., Willett, M. and Morley, S.J. Published:2014Publication:Cell CycleVolume:13, (16)Page Range:2517-2525doi:10.4161/15384101.2014.941747 Phosphorylation of eIF4GII and 4E-BP1 in response to nocodazole treatment: a reappraisal of translation initiation during mitosis - Coldwell, Mark J., Cowan, Joanne L., Vlasak, Markete, Mead, Abbie, Willett, Mark, Perry, Lisa S. and Morley, Simon J. Published:2013Publication:Cell CycleVolume:12, (23)Page Range:1-14doi:10.4161/cc.26588PMID:24091728 mRNA encoding WAVE-Arp2/3-associated proteins is co-localized with foci of active protein synthesis at the leading edge of MRC5 fibroblasts during cell migration - Willett, Mark, Brocard, Michele, Pollard, Hilary J. and Morley, Simon J. Published:2013Publication:Biochemical JournalVolume:452, (1)Page Range:45-55doi:10.1042/BJ20121803PMID:23452202 Translation initiation factors and active sites of protein synthesis co-localize at the leading edge of migrating fibroblasts - Willett, Mark, Brocard, Michele, Davide, Alexandre and Morley, Simon J. Published:2011Publication:Biochemical JournalVolume:438, (1)Page Range:217-227doi:10.1042/BJ20110435PMID:21539520 Localization of ribosomes and translation initiation factors to talin/beta3-integrin-enriched adhesion complexes in spreading and migrating mammalian cells - Willett, Mark, Pollard, Hilary J., Vlasak, Markete and Morley, Simon J. Published:2010Publication:Biology of the CellVolume:102, (5)Page Range:265-276doi:10.1042/BC20090141PMID:19929852