Howlin, Robert P. - University of Southampton - Discipline of Biological Sciences

个人简介

Career history 2009-present: Postdoctoral Researcher. University of Southampton, UK. Academic qualifications 2005-2009: PhD. University of Southampton, UK. 2002-2005: BSc in Biomedical Sciences. University of Durham, UK. My background is in microbial decontamination and novel biofilm intervention strategies in a biomedical setting. My current project, funded by the NIHR Respiratory Biomedical Research Unit, involves the investigating the role and application of nitric oxide as a novel adjunctive therapy in chronic infections such as cystic fibrosis.

研究领域

My interests include microbial decontamination & novel anti-biofilm intervention methods the role and application of nitric oxide (NO) in the dispersal of bacterial biofilms in cystic fibrosis and other biofilm related diseases the development of novel, targeted NO donor molecules as therapeutic interventions (a collaboration with University of Wollongong and UNSW) investigating the methods by which different bacterial species interact in the CF lung the role of biofilms in ventilator assisted pneumonia (VAP)

近期论文

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Effects of loading concentration, blood and synovial fluid on antibiotic release and anti-biofilm activity of bone cement beads - Dusane, Devendra, Diamond, Scott, Knecht, Cory, Farrar, Nicholas, Peters, Casey, Howlin, Robert, Swearingen, Matthew, Calhoun, Jason, Plaut, Roger D., Nocera, Tanya, Granger, Jeffrey and Stoodley, Paul Published:2017Publication:Journal of Controlled ReleasePage Range:1-28doi:10.1016/j.jconrel.2017.01.005 Biofilm prevention of gram-negative bacterial pathogens involved in periprosthetic infection by antibiotic-loaded calcium sulfate beads in vitro - Howlin, Robert P., Winnard, Chris, Frapwell, Connor J., Cooper, John J., Aiken, Sean S. and Stoodley, Paul Published:2016Publication:Biomedical MaterialsVolume:12, (1)Page Range:1-10doi:10.1088/1748-605X/12/1/015002 Prevention of Propionibacterium acnes biofilm formation in prosthetic infections in vitro - Howlin, Robert, Winnard, Chris, Angus, Elizabeth, Frapwell, Connor, Webb, Jeremy, Cooper, John, Aiken, Sean, Bishop, Julie and Stoodley, Paul Published:2016Publication:Journal of Shoulder and Elbow SurgeryPage Range:1-33 Development of X-ray micro-focus computed tomography to image and quantify biofilms in central venous catheter models in vitro - Niehaus, Wilmari, Howlin, Robert, Johnston, David A., Bull, Daniel, Jones, Gareth L., Calton, Elizabeth, Mavrogordato, Mark, Clarke, Stuart, Thurner, Philipp, Faust, Saul and Stoodley, Paul Published:2016Publication:MicrobiologyVolume:162Page Range:1629-1640doi:10.1099/mic.0.000334PMID:27384949 Parallel evolution in streptococcus pneumonia biofilms - Churton, Nicholas W.V., Misra, Raju V., Howlin, Robert, Allan, Raymond N., Jefferies, Johanna, Faust, Saul N., Gharbia, Saheer E., Edwards, Richard J., Clarke, Stuart C. and Webb, Jeremy S. Published:2016Publication:Genome Biology and EvolutionVolume:8, (5)Page Range:1316-1326doi:10.1093/gbe/evw072