Przewloka, Marcin R - University of Southampton - Discipline of Biological Sciences

个人简介

Career History 2016-present: Lecturer in Systems Biology; University of Southampton. 2005-2016: Research Associate; Department of Genetics, University of Cambridge, Cambridge, UK. 2003-2005: Research Associate; Department of Cell Biology, Albert Einstein College of Medicine, New York, USA 2000-2003: Postdoctoral Research Associate; Bioscience Division, Los Alamos National Laboratory, New Mexico, USA Academic Qualifications 2000: PhD, Department of Biology, University of Warsaw, Poland. 1995: MSc, Department of Biology, University of Warsaw, Poland.

研究领域

Faithful transmission of the genetic material to daughter cells is key to maintain genomic integrity at a cellular and organismal level. For this to happen proper chromosome condensation and segregation must occur in a controlled and coordinated manner. Chromosome segregation errors may potentially lead to inheritable abnormalities with severe consequences. Also, aneuploidy and chromosome instability, which arise from chromosomal aberrations, are hallmarks of cancer cells. It is therefore very important to understand mechanisms governing formation of chromosomes and their accurate segregation during cell division.

近期论文

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Network of protein interactions within the Drosophila inner kinetochore - Richter, Magdalena M., Poznanski, Jaroslaw, Zdziarska, Anna, Czarnocki-Cieciura, Mariusz, Lipinszki, Zoltan, Dadlez, Michal, Glover, David M. and Przewloka, Marcin R. Published:2016Publication:Open BiologyVolume:6, (2)Page Range:1-18doi:10.1098/rsob.150238PMID:26911623 DAPPER: a data-mining resource for protein-protein interactions - Haider, Syed, Lipinszki, Zoltan, Przewloka, Marcin R., Ladak, Yaseen, D'Avino, Pier Paolo, Kimata, Yuu, Lio', Pietro and Glover, David M. Published:2015Publication:BioData MiningVolume:8, (30)Page Range:1-8doi:10.1186/s13040-015-0063-3PMID:26405458 Establishment of centromeric chromatin by the CENP-A assembly factor CAL1 requires FACT-mediated transcription - Chen, Chin-Chi, Bowers, Sarion, Lipinszki, Zoltan, Palladino, Jason, Trusiak, Sarah, Bettini, Emily, Rosin, Leah, Przewloka, Marcin R., Glover, David M., O'Neill, Rachel J. and Mellone, Barbara G. Published:2015Publication:Developmental CellVolume:34, (1)Page Range:73-84doi:10.1016/j.devcel.2015.05.012PMID:26151904 The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins - Edlich-Muth, Christian, Artero, Jean-Baptiste, Callow, Phil, Przewloka, Marcin R., Watson, Aleksandra A., Zhang, Wei, Glover, David M, Debski, Janusz, Dadlez, Michal, Round, Adam R., Forsyth, V. Trevor and Laue, Ernest D. Published:2015Publication:Journal of Molecular BiologyVolume:427, (10)Page Range:1949-1963doi:10.1016/j.jmb.2015.03.010PMID:25813344 Centromeric binding and activity of Protein Phosphatase 4 - Lipinszki, Zoltan, Lefevre, Stephane, Savoian, Matthew S., Singleton, Martin R., Glover, David M. and Przewloka, Marcin R. Published:2015Publication:Nature CommunicationsVolume:6, (5894)Page Range:1-13doi:10.1038/ncomms6894PMID:25562660