Bell, Christopher - University of Southampton - Discipline of Biological Sciences

个人简介

Dr. Christopher Bell investigates how analysis of the epigenome, the chemical modifications and packaging of the genome, can inform us about the susceptibilities and consequences of common human diseases; such as Type 2 Diabetes. Career history 2014-2015: Post Doctoral Research Fellow (Prof. Tim Spector. King’s College London, UK. 2008-2014: Post Doctoral Research Fellow (Prof. Stephan Beck. UCL Cancer Institute, London, UK. 2005-2008: Genetic Pathology Registrar, Prince of Wales Hospital, Sydney, Australia. 2001-2005: PhD in Genomics (Prof. Philippe Froguel. Imperial College London, UK.

研究领域

Epigenomic Medicine Dr. Christopher Bell’s research uses computational biology, statistical genomics, and epigenetics to further understand common human diseases.

近期论文

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Higher naevus count exhibits a distinct DNA methylation signature in healthy human skin: implications for melanoma - Roos, Leonie, Sandling, Johanna, Bell, Christopher, Glass, Daniel, Mangino, Massimo, Deloukas, Panos, Bataille, Veronique and Bell, Jordana Published:2016Publication:Journal of Investigative DermatologyPage Range:1-37doi:10.1016/j.jid.2016.11.029 Insights in human epigenomic dynamics through comparative primate analysis - Bell, Christopher G. Published:2016Publication:GenomicsPage Range:1-11doi:10.1016/j.ygeno.2016.09.003PMID:27702613 Novel regional age-associated DNA methylation changes within human common disease-associated loci - Bell, Christopher G., Xia, Yudong, Yuan, Wei, Gao, Fei, Ward, Kirsten, Roos, Leonie, Mangino, Massimo, Hysi, Pirro, Bell, Jordana, Wang, Jun and Spector, Tim Published:2016Publication:Genome BiologyVolume:17, (193)Page Range:1-14doi:10.1186/s13059-016-1051-8 The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling - Maiarù, Maria , Tochik, Keri K., Cox, Marc B., Annan, Leonette V., Bell, Christopher G., Feng, Xixi , Hausch, Felix and Géranton, Sandrine M. Published:2016Publication:Science Translational MedicineVolume:8, (325)Page Range:1-29doi:10.1126/scitranslmed.aab3376PMID:26865567 Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs - Roos, L., van Dongen, J., Bell, C.G., Burri, A., Deloukas, P., Boomsma, D., Bell, J. and Spector, T. Published:2016Publication:Clinical EpigeneticsVolume:8, (7)Page Range:1-16doi:10.1186/s13148-016-0172-yPMID:26798410