个人简介

1998–2002 Research Associate at Department of Chemistry, School of Science, The University of Tokyo 2002–2005 Lecturer at Department of Chemistry, School of Science, The University of Tokyo 2005–2007 Associate Professor, Department of Molecular Structure, Institute for Molecular Science 2007– Professor, Department of Chemistry, School of Science, The University of Tokyo Awards: 2004 The Chemical Society of Japan Award for Young Chemists 2005 Young Scientists Award from Minister of MEXT (Ministry of Education, Culture, Science and Technology) 2011 Japan Society for the Promotion of Science (JSPS) Prize

研究领域

Analytical Chemistry/Protein Chemistry

(1) Development of methods for imaging biomolecules in living subjects (2) Development of methods for controlling biomolecules in living cells (3) Identification of functional biomolecules screened from a cDNA library (4) Development of the methods for high-throughput chemical library screening

近期论文

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Cyclic Luciferase for Real-Time Sensing of Caspase-3 Activities in Living Mammals, A. Kanno, Y. Yamanaka, H. Hirano, Y. Umezawa and T. Ozawa, Angew. Chem. Int. Ed. 2007, 46, 7595. Imaging Dynamics of Endogenous Mitochondrial RNA in Single Living Cells, T. Ozawa, Y. Natori, M. Sato and Y. Umezawa, Nature Methods, 2007, 4, 413. A Minimal Peptide Sequence That Targets Fluorescent and Functional Proteins into the Mitochondrial Intermembrane Space, T. Ozawa, Y. Natori, Y. Sako, H. Kuroiwa, T. Kuroiwa and Y. Umezawa, ACS. Chem. Biol., 2007, 2, 176. A Genetically Encoded Optical Probe for Detecting Release of Proteins from Mitochondria toward Cytosol in Living Cells and Animals, A. Kanno, T. Ozawa and Y. Umezawa, Anal. Chem., 2006, 78, 8076. A High-Throughput Screening of Genes that Encode Proteins Transported into the Endoplamsic Reticulum in Mammalian Cells, T. Ozawa, K. Nishitani, Y. Sako, Y. Umezawa, Nucleic. Acids Res., 2005, 33, e34. High-Throughput Sensing and Noninvasive Imaging of Protein Nuclear Transport by Using Reconstitution of Split Renilla Luciferase, S. B. Kim, T. Ozawa, S. Watanabe, Y. Umezawa, Proc. Natl. Acad. Sci. USA., 2004, 101, 11542. A genetic Approach to Identifying Mitochondrial Proteins, T. Ozawa, Y. Sako, M. Sato, T. Kitamura, and Y. Umezawa, Nature Biotechnol., 2003, 21, 287. Fluorescent Indicators for Imaging Protein Phosphorylation in Single Living Cells, M. Sato, T. Ozawa, K. Inukai, T. Asano, and Y. Umezawa, Nature Biotechnol., 2002, 20, 287. Split Luciferase as an Optical Probe for Detecting Protein-Protein Interactions in Mammalian Cells Based on Protein Splicing, T. Ozawa, A. Kaihara, M. Sato, K. Tachihara and Y. Umezawa, Anal. Chem., 2001, 73, 2516.