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个人简介

Professor John Primrose is Professor of Surgery at the University of Southampton, a post he has held since 1994. He trained in Glasgow and Leeds where he was Lecturer and then Senior Lecturer in Surgery. His clinical interest is in cancer, particularly hepatobiliary (HPB) cancer and Southampton is a large tertiary referral centre for HPB disease. It is the largest laparoscopic HPB centre in the UK. He is Director of the NIHR Hampshire and Isle of Wight Comprehensive Local Research Network and in that role he is committed to promoting a research led NHS, and currently Chair of the National Cancer Research Institute Upper GI Clinical Studies Group. He is Chief Investigator of several major national and international clinical trials and has served on a large number of national bodies particularly Cancer Research UK funding committees. His research interests focus on large clinical trials in cancer and translational surgical oncology. He is Chief Investigator of several major national and international clinical trials and has served on a large number of national bodies particularly Cancer Research UK funding committees. His research interests focus on large clinical trials in cancer and translational surgical oncology. He was recently elected Vice President (President Elect) of the Association of Surgeons of Great Britain and Ireland, the principle membership organization for surgeons in the British Isles.

研究领域

Professor Primrose’s research is in gastrointestinal cancer, clinical and translational and Health Services Research. The focus is on improving outcomes for patients undergoing surgical treatment for cancer. This is being achieved through devising and undertaking large scale national and international trials. All the studies are associated with tissue collections with a view to the development of biomarkers which will have prognostic value and may also predict response to therapy.

近期论文

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Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1 - Garcia, Edwin, Hayden, Annette, Birts, Charles, Britton, Edward, Cowie, Andrew, Pickard, Karen, Mellone, Massimiliano, Choh, Clarisa, Derouet, Mathieu, Duriez, Patrick, Noble, Fergus, White, Michael J., Primrose, John, Strefford, Jonathan C., Rose-Zerilli, Matthew, Thomas, Gareth, Ang, Yeng, Sharrocks, Andrew D., Fitzgerald, Rebecca C. and Underwood, Timothy J. Published:2016Publication:Scientific reportsVolume:6, (32417)Page Range:1-12doi:10.1038/srep32417PMID:27600491 Propensity score-based analysis of outcomes of laparoscopic versus open liver resection for colorectal metastases. - Cipriani, F., Rawashdeh, M., Stanton, L., Armstrong, T., Takhar, A., Pearce, N.W., Primrose, J. and Abu Hilal, M. Published:2016Publication:British Journal of SurgeryVolume:103, (11)Page Range:1504-12doi:10.1002/bjs.10211PMID:27484847 Patterns of progression, treatment of progressive disease and post-progression survival in the New EPOC study - Pugh, Sian A., Bowers, Megan, Ball, Alexandre, Falk, Stephen, Finch-Jones, Meg, Valle, Juan W., O'Reilly, Derek A., Siriwardena, Ajith K., Hornbuckle, Joanne, Rees, Myrddin, Rees, Charlotte, Iveson, Tim, Hickish, Tamas, Maishman, Tom, Stanton, Louise, Dixon, Elizabeth, Corkhill, Andrea, Radford, Mike, Garden, O. James, Cunningham, David, Maughan, Tim S., Bridgewater, John A. and Primrose, John N. Published:2016Publication:British Journal of CancerVolume:115Page Range:420-424doi:10.1038/bjc.2016.208PMID:27434036 Outcome and learning curve in 159 consecutive patients undergoing total laparoscopic hemihepatectomy - van der Poel, Marcel J., Besselink, Marc G., Cipriani, Federica, Armstrong, Thomas, Takhar, Arjun S., van Dieren, Susan, Primrose, John N., Pearce, Neil W. and Abu Hilal, Mohammad Published:2016Publication:JAMA SurgeryVolume:151, (10)Page Range:923-928doi:10.1001/jamasurg.2016.1655PMID:27383568 Site and stage of colorectal cancer influence the likelihood and distribution of disease recurrence and postrecurrence survival: data from the FACS randomized controlled trial - Pugh, Siân A., Shinkins, Bethany, Fuller, Alice, Mellor, Jane, Mant, David and Primrose, John N. Published:2016Publication:Annals of SurgeryVolume:263Page Range:1143-7doi:10.1097/SLA.0000000000001351PMID:26135689

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