Harvey, Nicholas - University of Southampton

个人简介

BA (Hons), Physiological Sciences, University of Oxford 1995 MB BChir, University of Cambridge 1997 MA, Physiological Sciences, University of Oxford 2003 PhD, University of Southampton 2007 MRCP, Medicine, RCP 2001 CCT, Rheumatology, PMETB 2008 FRCP, Medicine, RCP 2015

研究领域

Prof Harvey’s work has focussed on investigating the factors which influence bone development early in life, a subject which has the potential for great public health impact. His contributions include: Confirmation that low maternal 25(OH)-vitamin D concentration during pregnancy is associated with reduced bone mass in the offspring (Harvey et al.,JCEM 2008; Javaid et al.,Lancet 2006; Mahon et al.,JBMR 2010); Confirmation that maternal exercise, fat mass and behaviour during pregnancy influence bone mass (Harvey et al.,JDOHAD 2010) and body composition (Harvey et al.,JCEM 2007; Harvey et al., JCEM 2014) in the offspring; Demonstration of links between daily physical activity levels, calcium intake and bone strength in a community population of children (Harvey et al.,OI 2012); Description of relationships between growth in utero, measured using gestational ultrasound scanning, and skeletal development in childhood (Harvey et al.,JBMR 2010, Harvey et al.,PPE 2012; Harvey et al.,Ped Res 2013); Elucidation of aetiological factors underlying these epidemiological observations, such as the relationship between placental calcium transporters and offspring bone mass (Martin et al.,Bone 2007), and epigenetic regulation of genes in umbilical cord (Harvey et al.,CTI 2012; Harvey et al., JBMR 2014); Demonstration that bariatric surgery does not appear to increase fracture risk, at least up to 5 years post-surgery (Lalmohamed et al., BMJ 2012).

近期论文

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Bone mineral content and areal density, but not bone area, predict incident fracture risk: a comparative study in a UK prospective cohort - Curtis, Elizabeth, Harvey, Nicholas, D'angelo, Stefania, Cooper, C.S., Ward, Kate, Taylor, P., Pearson, G. and Cooper, Cyrus Published:2016Publication:Archives of Osteoporosis Determinants of the maternal 25-hydroxyvitamin D response to vitamin D supplementation during pregnancy - Moon, R.J., Harvey, N.C., Cooper, C., D'angelo, S., Crozier, S.R., Inskip, H.M., Schoenmakers, I., Prentice, A., Arden, N.K., Bishop, N.J., Carr, A., Dennison, E.M., Eastell, R., Fraser, R., Gandhi, S.V., Godfrey, K.M., Kennedy, S., Zulf Mughal, M., Papageorghiou, A.T., Reid, D.M., Robinson, S.M and Javaid, M.K. Published:2016Publication:Journal of Clinical Endocrinology & MetabolismPage Range:1-9doi:10.1210/jc.2016-2869PMID:27788053 The use of incretins and fractures - a meta-analysis on population-based real life data - Driessen, J.H.M., de Vries, F., van Onzenoort, H., Harvey, N.C., Neef, C., van den Bergh, J., Vestergaard, P. and Henry, R.M.A. Published:2016Publication:British Journal of Clinical PharmacologyPage Range:1-10doi:10.1111/bcp.13167