Griffiths, Gareth - University of Southampton

个人简介

Professor Griffiths was appointed to the Chair of Clinical Trials and Director of the Southampton Clinical Trials Unit in July 2014. Having graduated with a BSc in Biological Sciences (joint statistics and biology) at Reading University, a MSc in Statistics in applications in Medicine at Southampton University and later a Phd in bladder cancer clinical trials at Cardiff University, has spent the majority of his career in the area of clinical trials. He has held the position of senior statistician/scientific lead at the MRC Clinical Trials Unit, London, Director of the National Institute for Social Care and Health Research (NISCHR - Wales) Cancer Registered Research Group and Director and founder of the Wales Cancer Trials Unit in Cardiff before his current appointment at Southampton University. Professor Griffiths is the Director of the UKCRC registered Southampton Clinical Trials Unit (CTU) which is based within the Faculty of Medicine. Southampton CTU is Cancer Research UK (CRUK) core funded and receives National Institute for Health Research (NIHR) clinical trials unit support funding.

研究领域

Professor Griffiths’s area of expertise and research is in the area of clinical trials. His Clinical Trials Unit undertakes research in cancer and non-cancer, using clinical trials, and other well design studies, to investigate new interventions (drug and non-drug). Within cancer his interests lie in cancer therapies (including novel agents), primary care oncology and supportive care. Professor Griffiths is internationally recognised in the area of bladder cancer clinical trials and nationally in upper gastro-intestinal cancer and palliative and supportive care. Professor Griffiths has been involved in the development of over 40 clinical trials (phase I/II-III) and associated studies and has represented CRUK on numerous occasions at national and international meetings (e.g. US National Institute of Health in developing global trials in rare cancers) and have lead statistical task forces to advise CRUK funding committees on appropriate clinical trials designs to fund.

近期论文

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Health-related guality of Life in SCALOP, a randomized phase 2 trial comparing chemoradiation therapy regimens in locally advanced pancreatic cancer - Hurt, Christopher N., Mukherjee, Somnath, Bridgewater, John, Falk, Stephen, Crosby, Tom, McDonald, Alec, Joseph, George, Staffurth, John, Abrams, Ross A., Blazeby, Jane M., Bridges, Sarah, Dutton, Peter, Griffiths, Gareth, Maughan, Tim and Johnson, Colin Published:2015Publication:International Journal of Radiation Oncology*Biology*PhysicsVolume:93, (4)Page Range:810-818doi:10.1016/j.ijrobp.2015.08.026 Activity, safety, and feasibility of cidofovir and imiquimod for treatment of vulval intraepithelial neoplasia (RT3VIN): a multicentre, open-label, randomised, phase 2 trial - Tristram, Amanda, Hurt, Christopher N., Madden, Tracie, Powell, Ned, Man, Stephen, Hibbitts, Sam, Dutton, Peter, Jones, Sadie, Nordin, Andrew J., Naik, Raj, Fiander, Alison and Griffiths, Gareth Published:2014Publication:The Lancet OncologyVolume:15, (12)Page Range:1361-1368doi:10.1016/S1470-2045(14)70456-5PMID:25304851