Galea, Ian - University of Southampton

个人简介

Ian Galea is an Associate Professor in Experimental Neurology within Medicine at the University of Southampton. He leads the Southampton Clinical and Experimental Neurology Team (SCENT), a multidisciplinary group of investigators studying inflammatory and haemorrhagic brain conditions. The team has laboratory expertise in cell culture, immunochemistry, molecular techniques and preclinical models, and clinical translational expertise in clinical assessment, diagnostic assays and neuroimaging.

研究领域

His research concerns the brain’s immune system, and its response to infections, inflammation and haemorrhage, with implications for diseases such as multiple sclerosis and subarachnoid haemorrhage. As a clinician scientist he works across clinical and laboratory areas. He is a consultant neurologist with a specialist interest in neuroinflammatory disease. In his early scientific career, he studied cerebral perivascular macrophages at the blood-brain barrier and described a novel pathway of CD8 T cell entry into the brain. This formed the basis for his post-doctoral work, during which he studied the haemoglobin-scavenging system in the brain after subarachnoid haemorrhage and CD8 T cell-mediated brain disease. He was appointed to his current post in 2013.

近期论文

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Lymphopenia in treatment-naive relapsing multiple sclerosis - Lim, Zhi Wei, Elwood, Elliot, Naveed, Hammad and Galea, Ian Published:2016Publication:Neurology: Neuroimmunology & NeuroinflammationPage Range:1-9 How do people with multiple sclerosis experience prognostic uncertainty and prognosis communication? A qualitative study - Dennison, Laura, McCloy-Smith, Ellen, Bradbury, Katherine and Galea, Ian Published:2016Publication:PLoS ONEPage Range:1-24 Outcome and biomarker analysis from a multi-centre phase 2 study of ipilimumab in combination with carboplatin and etoposide (ICE) as first line therapy for extensive stage small cell lung cancer - Arriola, E., Wheater, M., Galea, I., Cross, N., Maishman, T., Hamid, D., Stanton, L., Cave, J., Geldart, T., Mulatero, C., Potter, V., Dansen, S., Woll, P.J., Griffiths, R., Nolan, L. and Ottensmeier, C. Published:2016Publication:Journal of Thoracic OncologyPage Range:1-27doi:10.1016/j.jtho.2016.05.028PMID:27296105 The blood-brain barrier in systemic inflammation - Varatharaj, Aravinthan and Galea, Ian Published:2016Publication:Brain Behavior and ImmunityPage Range:1-12doi:10.1016/j.bbi.2016.03.010PMID:26995317