Collins, Andrew - University of Southampton

个人简介

Professor Collins began his academic career in Southampton in 1989 and was appointed head of the Genetic Epidemiology and Bioinformatics research group in 2002. He has developed diverse research projects spanning non-disjunction and aberrant recombination patterns, bioinformatic prediction of imprinted and disease genes, biological properties of chromosomes, segregation analysis, autozygosity mapping, and linkage mapping studies for various diseases, genome-wide association mapping and next generation sequencing. He is currently working on the genetic basis of cleft lip and palate, breast cancer and leukemia, along with methodology for analysis of next generation sequencing data and patterns of linkage disequilibrium in human and non-human genomes.

研究领域

1. The development and application of machine learning methods for the identification of the genetic basis of early onset breast cancer. 2. Development of bioinformatic analyses of next-generation sequencing data and application to cancer genomes. 3. Approaches to meta-analysis to determine the genetic basis of risk and he identification of genetic factors influencing survival in early onset breast cancer. 4. The genetic basis of paediatric inflammatory bowel disease.

近期论文

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Deleterious coding variants in multi-case families with non-syndromic cleft lip and/or palate phenotypes - Pengelly, Reuben J., Arias, Liliana, Martinez, Julio, Upstill-Goddard, Rosanna, Seaby, Eleanor G., Gibson, Jane, Ennis, Sarah, Collins, Andrew and Briceno, Ignacio Published:2016Publication:Scientific ReportsVolume:6Page Range:30457 Commercial chicken breeds exhibit highly divergent patterns of linkage disequilibrium - Pengelly, Reuben J., Gheyas, Almas A., Kuo, Richard, Mossotto, Enrico, Seaby, Eleanor G., Burt, David W., Ennis, Sarah and Collins, Andrew Published:2016Publication:HeredityVolume:117, (5)Page Range:375-382doi:10.1038/hdy.2016.47PMID:27381324 Aarskog-Scott syndrome: phenotypic and genetic heterogeneity - Jabalameli, M. Reza, Briceno, Ignacio, Julio, Martinez, Pengelly, Reuben, Ennis, Sarah and Collins, Andrew Published:2016Publication:AIMS Genetics Volume:3, (1)Page Range:49-59doi:10.3934/genet.2016.1.49