Clarke, Stuart - University of Southampton

个人简介

Dr Clarke initially trained in medical microbiology in Berkshire, gaining a MSc in Medical Microbiology from the University of Surrey, before studying for a PhD in Molecular Microbiology at the University of Leicester. He was Director of the Scottish Meningococcus and Pneumococcus Reference Laboratory in Glasgow between 1998 and 2004. He then took up specialist training in public health in Hampshire and was awarded an MSc in Public Health from the London School of Hygiene and Tropical Medicine in 2005. He became a Fellow of the Royal College of Pathologists and a Fellow of the Faculty of Public Health of the Royal Colleges of Physicians of the United Kingdom in 2007. In 2009, Dr Clarke won the Bupa Foundation's award of ‘best emerging medical researcher in the UK’ for his work on the molecular epidemiology of pneumococcal infection around the introduction of pneumococcal conjugate vaccines. ResearchResponsibilitiesPublicationsTeachingContact

研究领域

Dr Clarke developed his independent research career in 1999 when he was Director of the Scottish Meningococcus and Pneumococcus Reference Laboratory. His research focuses on the molecular epidemiology of Streptococcus pneumoniae and other vaccine-preventable bacterial infections, particularly in relation to polysaccharide conjugate vaccines. Dr Clarke was involved in the national meningococcal carriage study, led by Professors Martin Maiden and James Stuart, which was mainly funded by the Wellcome Trust. His laboratory led on the Scottish component of the study jointly with Health Protection Scotland. His laboratory was the first to introduce automated methods for multi-locus sequence typing (MLST) and was also the first reference laboratory in the world to introduce the method as a routine clinical service. He has since been involved in various pneumococcal and MenB carriage studies. The Southampton paediatric pneumococcal carriage study has been running for 10 years, since the introduction of pneumococcal conjugate vaccines in the UK.

近期论文

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Relationships between mucosal antibodies, non-typeable haemophilus influenzae (NTHi) infection and airway inflammation in COPD - Staples, Karl J., Taylor, Stephen, Thomas, Steve, Leung, Stephanie, Cox, Karen, Pascal, Thierry G., Ostridge, Kristoffer, Welch, Lindsay, Tuck, Andrew C, Clarke, Stuart C, Gorringe, Andrew and Wilkinson, Thomas Published:2016Publication:PLoS ONEPage Range:1-17doi:10.1371/journal.pone.0167250PMID:27898728 Pneumococcal conjugate vaccine implementation in middle-income countries - Tricarico, Serena, McNeil, Hannah C., Cleary, David W., Head, Michael G., Lim , Victor, Kok Seng Yap, Ivan, Chun Wie, Chong, Siang Tan, Cheng, Norazmi, Mohd Nor, Ismail, Aziah, Seong Guan Cheah, Eddy, Faust, Saul N., Jefferies, Johanna M.C., Roderick, Paul J., Moore, Michael, Yuen, Ho Ming, Newell, Marie-Louise, Mcgrath, Nuala, Webb, Jeremy, Doncaster, C. Patrick, Kraaijeveld, Alex R., Webb, Jeremy S. and Clarke, Stuart C. Published:2016Publication:PneumoniaPage Range:1-26 The State of ESKAPE in Malaysia - Mcneil, Hannah C., Lean, Soo-Sum, Lim, Victor and Clarke, Stuart C. Published:2016Publication:International Journal of Antimicrobial AgentsPage Range:1-4doi:10.1016/j.ijantimicag.2016.08.011