Stulz, Eugen - University of Southampton

个人简介

Eugen Stulz graduated from the University of Bern (Switzerland) in 1994, where he subsequently studied for a Ph.D. under the supervision of Prof. Christian J. Leumann. His thesis was concerned with the evaluation of artificial nucleases based on zirconium(iv) complexes. In 1999, he moved to Cambridge (UK) as a Swiss National Science Foundation (SNF) Postdoctoral fellow to the group of Prof. Jeremy K. M. Sanders, working in the field of supramolecular chemistry and dynamic combinatorial libraries using phosphine-substituted porphyrins. During this time, he also held a part-time teaching position at Anglia Polytechnic University, and an Advanced Research position. In 2003, he moved to the University of Basel (Switzerland) as a Lecturer (Habilitand) with a Fellowship of the Treubel Foundation Basel and started his independent research in the field of supramolecular chemistry using DNA as scaffold for novel functional molecules. In 2006, he was appointed Lecturer in Chemistry at the University of Southampton, promoted Senior Lecturer in 2010 and Associate Professor in 2014. In addition to >60 research papers, Eugen Stulz has been author of several invited review articles, of an invited book chapter contribution, and has been invited editor of a special theme issue on DNA nanotechnology in CSR in 2011. In 2003 he was also awarded the SYNTHESIS/SYNLETT Journal Award by Thieme, Germany. Currently he is editing a book for Wiley “DNA in Supramolecular Chemistry and Nanotechnology” (to be published 2015).

研究领域

The general research interests in the Stulz group are concerned with bio-nanotechnology using chemically modified DNA as template. Most notably we have pioneered the use of porphyrin-DNA for applications in energy / electron transfer, DNA structure analysis and as lipid anchor. General aspects of DNA origami technology play a key role in our research, and functional DNA is being explored in this aspect. The research, which can be termed DNA nanoarchitectonics, is highly interdisciplinary, and reaches into materials science, nanotechnology, analytical science, and into biological sciences. We are also interested in nanotechnology using silver nanoprisms as sensors and as energy converting systems. Together with Engineering, we are developing the use of flow-through micro reactor technology for the reliable synthesis of nanoparticles. These are further functionalised for embedding in polymers, or conjugation to bio-molecules such as DNA or proteins.

近期论文

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Construction of DNA–polymer hybrids using intercalation interactions - Wilks, Thomas R., Pitto-Barry, Anaïs, Kirby, Nigel, Stulz, Eugen and O'Reilly, Rachel K. Published:2014Publication:Chemical CommunicationsVolume:50Page Range:1338-1340doi:10.1039/C3CC48726A Lipid-bilayer-spanning DNA nanopores with a bifunctional porphyrin anchor - Burns, Jonathan R., Göpferich, Kerstin, Wood, James, Thacker, Vivek V., Stulz, Eugen, Keyser, Ulrich F. and Howorka, Stefan Published:2013Publication:Angewandte Chemie International EditionVolume:52, (46)Page Range:12069-12072doi:10.1002/anie.201305765 Letter. Self-assembled DNA nanopores that span lipid bilayers - Burns, Jonathan R., Stulz, Eugen and Howorka, Stefan Published:2013Publication:Nano LettersVolume:13, (6)Page Range:2351-2356doi:10.1021/nl304147f DNA as supramolecular scaffold for functional molecules: progress in DNA nanotechnology - Bandy, Thomas J., Brewer, Ashley, Burns, Jonathan R., Marth, Gabriella, Nguyen, ThaoNguyen and Stulz, Eugen Published:2011Publication:Chemical Society ReviewsVolume:40, (1)Page Range:138-148doi:10.1039/b820255aPMID:20694258