Lough, John - Sunderland University - Department of Pharmacy, Health and Well-being

个人简介

Dr John Lough is Reader in Pharmaceutical Analysis in the Department of Pharmacy, Health and Well-Being. Through his strong pharmaceutical industry background built on his research and professional activities and early career, his work at the University of Sunderland has been characterised by activities that enhance student employability. He was very closely associated with the University’s highly regarded, pioneering BSc Chemical and Pharmaceutical Science programme. During a period of ‘modernisation’ of teaching provision he played a major role in the continuation of pharmaceutical sciences at undergraduate level through the BSc BioPharmaceutical Sciences programme and designed and subsequently led the MSc Drug Discovery and Development programme. He has also found time for >80 research publications, >100 invited external presentations, 31 successful PhD supervisions and editing or co-editing five books (“Chiral Liquid Chromatography”, Pharmaceutical and Biomedical Applications of Liquid Chromatography”, HPLC: Fundamental Principles and Practices”, “Chirality in the Natural and Applied Sciences” and “Drug Stereochemistry (3rd Edition)”). He has obtained £750K in external research funding and made contributions to successful departmental funding bids. He is a longstanding member of The Chromatographic Society (President, 2007-2009) and the British Pharmacopoeia Expert Advisory Group MC1, has delivered short courses nationally and internationally, consulted widely in the UK and on chiral patent cases in North America, chaired the 8th International Symposium on Chiral Discrimination and served on 7 other international symposium committees (also Secretary, Permanent Scientific Committee, International Symposium on Chromatography (2010-2016). He has served on editorial advisory boards for four international journals and currently referees for 10 journals.

研究领域

From an ICI-sponsored PhD and 7.5 years spent with Beecham Pharmaceuticals in his early career, to big pharma collaborations during his time in academia, his research interests have always been orientated towards industrial applications. In the general area of pharmaceutical and biomedical analysis this has included a varied range of funded studies: The exploitation of achiral derivatisation in chiral separations Studies in low dispersion chromatography Use of on-column sample focusing in drug bioanalysis Chiral drug bioanalysis Biomedical applications of capillary electrophoresis Pharmaceutical applications of capillary electrochromatography The evaluation and exploitation of orthogonal stationary phase selectivity in liquid chromatography

近期论文

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Perera, Wimal and Lough, John (2011) Assessment of chiral stationary phases for suitability for combined enantiomeric impurity/ related substances assays. Journal of Chromatography A, 1218 (48). pp. 8655-8663. ISSN 0021-9673 Singh, Nagendra, Day, P, Katta, V R, Mohammed, G P and Lough, John (2010) LC Purity and Related Substances Screening for Mephedrone. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1209-1210. ISSN 2042-7158 Imrie, G A, Noctor, T A G and Lough, John (2009) Drug Bioanalysis by LC-MS: some pragmatic solutions to commonly occurring problems. Chromatography Today, 2 (2). pp. 27-30. ISSN 1752-8070 Whiteley, P, Waring, R, Williams, Lee, Klovrza, L, Nolan, F, Smith, S, Farrow, M, Dodou, Kalliopi, Lough, John and Shattock, Paul (2006) Spot urinary creatinine excretion in pervasive developmental disorders. Pediatrics International, 48 (3). 292-297.. ISSN 1442-200X Lough, John, Shabir, G A, Arain, S A and Shar, G Q (2006) Method development and validation of preservatives (Phenylformic acid, 2,4-hexadienoic acid, methyl 4-hydroxybenzoate and propyl 4-hydroxybenzoate) by HPLC. Journal of Liquid Chromatography, 29 (9). pp. 1233-1333. ISSN 01483919 Lough, John, Simmonds, E L and Gray, Martin R (2006) Evaluation of LC-MS for the analysis of cleaning verification samples. Journal of Pharmaceutical and Biomedical Analysis, 40 (3). pp. 631-638. ISSN 07317085