Allwood, Daniel - Sheffield Hallam University - Department of Biosciences and Chemistry

个人简介

Danny joined Sheffield Hallam University from the University of Cambridge, where he undertook a PhD (2008-2012) and post-doctoral research (2012-2015) with Professor Steven V. Ley CBE FRS. Prior to this, he attained his undergraduate degree at the University of Warwick (2004-2008). His current research programme is focused on the development of practical synthetic and catalytic organic transformations; in particular, sp2-sp3 and sp3-sp3 carbon-carbon bond formation.

近期论文

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R.R. Merchant, D.M. Allwood, D.C. Blakemore and S.V. Ley, Regioselective preparation of saturated spirocyclic and ring-expanded fused pyrazoles, J. Org. Chem. 2014, 79, 8800-8811. D.M. Allwood, D.L. Browne and S.V. Ley, Synthesis and use of a trifluoromethylated azomethine ylide precursor: Ethyl 1-benzyl-trans-5-(trifluoromethyl)pyrollidine-3-carboxylate, Org. Synth. 2014, 91, 162-174. T.M. Beale, D.M. Allwood, A. Bender, P.J. Bond, J.D. Brenton, D.S. Charnock-Jones, S.V. Ley, R.M. Myers, J.W. Shearman, J. Temple, J. Unger, C.A. Watts and J. Xian, A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles, ACS Med. Chem. Lett. 2012, 3, 177-181. BATTILOCCHIO, Claudio, FEIST, Florian, HAFNER, Andreas, SIMON, Meike, TRAN, Duc, ALLWOOD, Daniel, BLAKEMORE, David and LEY, Steven (2016). Iterative reactions of transient boronic acids enable sequential C–C bond formation. Nature Chemistry, 8 (4), 360-363. ROUQUET, Guy, MOORE, Dianna E., SPAIN, Malcolm, ALLWOOD, Daniel, BATTILOCCHIO, Claudio, BLAKEMORE, David C., FISH, Paul V., JENKINSON, Stephen, JESSIMAN, Alan S., LEY, Steven V., MCMURRAY, Gordon and STORER, R. Ian (2015). Design, synthesis, and evaluation of tetrasubstituted pyridines as potent 5-HT2CReceptor agonists. ACS Medicinal Chemistry Letters, 6 (3), 329-333.