个人简介
Medicinal organic chemist. Worked in design, synthesis and applications of photosensitisers since 1987. Particular interest in the application to infection control (photoantimicrobials). Book "Photosensitisers in Biomedicine" (Wiley) published in 2009. Photosensitiser design spin-out Pharmalucia, 2008-2013.
近期论文
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Wainwright M. 2017. Dyes, flies, and sunny skies: photodynamic therapy and neglected tropical diseases Coloration Technology, 133 :3-14 >DOI
Wainwright M, McLean A. 2017. Rational design of phenothiazinium derivatives and photoantimicrobial drug discovery Dyes and Pigments, 136 :590-600 >DOI
Wainwright M, Maisch T, Nonell S, Plaetzer K, Almeida A, Tegos GP, Hamblin MR. 2016. Photoantimicrobials-are we afraid of the light? The Lancet Infectious Diseases, >DOI
Brancini GTP, Rodrigues GB, Rambaldi MDSL, Izumi C, Yatsuda AP, Wainwright M, Rosa JC, Braga GÚL. 2016. The effects of photodynamic treatment with new methylene blue N on the: Candida albicans proteome Photochemical and Photobiological Sciences, 15 :1503-1513 >DOI
de Menezes HD, Tonani L, Bachmann L, Wainwright M, Braga GÚL, von Zeska Kress MR. 2016. Photodynamic treatment with phenothiazinium photosensitizers kills both ungerminated and germinated microconidia of the pathogenic fungi Fusarium oxysporum, Fusarium moniliforme and Fusarium solani Journal of Photochemistry and Photobiology B: Biology, 164 :1-12 >DOI
Fracarolli L, Rodrigues GB, Pereira AC, Massola Júnior NS, Silva-Junior GJ, Bachmann L, Wainwright M, Bastos JK, Braga GUL. 2016. Inactivation of plant-pathogenic fungus Colletotrichum acutatum with natural plant-produced photosensitizers under solar radiation Journal of Photochemistry and Photobiology B: Biology, 162 :402-411 >DOI
Wainwright M, O'Kane C, Rawthore S. 2016. Phenothiazinium photosensitisers XI. Improved toluidine blue photoantimicrobials Journal of Photochemistry and Photobiology B: Biology, 160 :68-71 >DOI
Spagnul C, Greenman J, Wainwright M, Kamil Z, Boyle RW. 2016. Synthesis, characterization and biological evaluation of a new photoactive hydrogel against Gram-positive and Gram-negative bacteria JOURNAL OF MATERIALS CHEMISTRY B, 4 :1499-1509 >DOI >Link
Wainwright M. 2016. Laser-guided magic bullets-A non-antibiotic answer to O'Neill Photodiagnosis and Photodynamic Therapy, 13 :A1-A2 >DOI
Tardivo JP, Wainwright M, Baptista M. 2015. Small scale trial of photodynamic treatment of onychomycosis in São Paulo Journal of Photochemistry and Photobiology B: Biology, 150 :66-68 >DOI
Wainwright M, Antczak J, Baca M, Loughran C, Meegan K. 2015. Phenothiazinium photoantimicrobials with basic side chains Journal of Photochemistry and Photobiology B: Biology, 150 :38-43 >DOI
Wainwright M. 2015. Tricyclic cationic chromophores as models for new photoantimicrobials Journal of the Brazilian Chemical Society, 26 :2390-2404 >DOI
Bacellar IOL, Pavani C, Sales EM, Itri R, Wainwright M, Baptista MS. 2014. Membrane damage efficiency of phenothiazinium photosensitizers Photochemistry and Photobiology, 90 :801-813 >DOI
Wainwright M. 2014. In defence of 'dye therapy' International Journal of Antimicrobial Agents, 44 :26-29 >DOI
Bacellar IOL, Pavani C, Baptista MS, Sales EM, Itri R, Wainwright M. 2014. Membrane damage efficiency of phenothiazinium photosensitizers Photochemistry and Photobiology, >DOI
de Menezes HD, Rodrigues GB, Teixeira SDP, Massola NS, Bachmann L, Wainwright M, Braga GUL. 2014. In vitro photodynamic inactivation of plant-pathogenic fungi Colletotrichum acutatum and Colletotrichum gloeosporioides with novel phenothiazinium photosensitizers Applied and Environmental Microbiology, 80 :1623-1632 >DOI
De Menezes HD, Pereira AC, Brancini GTP, De Leão HC, Massola Júnior NS, Bachmann L, Wainwright M, Bastos JK, Braga GUL. 2014. Furocoumarins and coumarins photoinactivate Colletotrichum acutatum and Aspergillus nidulans fungi under solar radiation Journal of Photochemistry and Photobiology B: Biology, 131 :74-83 >DOI
Wainwright M, Wainwright M. 2013. Photobactericides - a local option against MDR bacteria Antibiotics, 2 :182-190
Rodrigues GB, Dias-Baruffi M, Holman N, Wainwright M, Braga GUL. 2013. In vitro photodynamic inactivation of Candida species and mouse fibroblasts with phenothiazinium photosensitisers and red light Photodiagnosis and Photodynamic Therapy, 10 :141-149 >DOI
Wainwright M. 2013. Missed chance? Chemistry and Industry (London), 77 :36-39 >DOI
Rodrigues GB, Dias-Baruffi M, Braga GUL, Holman N, Wainwright M. 2012. In vitro photodynamic inactivation of Candida species and mouse fibroblasts with phenothiazinium photosensitisers and red light Photodiagnosis and Photodynamic Therapy, >DOI
Rodrigues GB, Ferreira LKS, Wainwright M, Braga GUL. 2012. Susceptibilities of the dermatophytes Trichophyton mentagrophytes and T. rubrum microconidia to photodynamic antimicrobial chemotherapy with novel phenothiazinium photosensitizers and red light Journal of Photochemistry and Photobiology B: Biology, 116 :89-94 >DOI
Sadek B, Ashoor A, Mansouri AA, Lorke DE, Nurulain SM, Petroianu G, Wainwright M, Oz M. 2012. N3,N7-diaminophenothiazinium derivatives as antagonists of α7-nicotinic acetylcholine receptors expressed in Xenopus oocytes Pharmacological Research,
Tardivo JP, Wainwright M, Baptista MS. 2012. Local clinical phototreatment of herpes infection in São Paulo Photodiagnosis and Photodynamic Therapy,
Wainwright M. 2012. Photodynamic medicine and infection control. J Antimicrob Chemother, 67 :787-788 >DOI >Link