Moore, Sharon - Liverpool John Moores University - School of Pharmacy and Biomolecular Sciences

个人简介

Sharon joined LJMU in September 2007 to teach analytical chemistry on a number of programs within the school (Applied Chemical and Pharmaceutical Science, Forensic Science and Pharmacy). Previously she was a postdoctoral researcher at the Open University working with in the field of diet and DNA damage. This research was carried out with Professor David Shuker and resulted in a number of publications. Sharon's expertise was in the measurement of DNA adducts and this continues to be an area of current interest. Degrees 2001, Open University, United Kingdom, PhD, Chemistry 1998, Open University, United Kingdom, BSc Hons, Chemistry

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Hemeryck LY, Moore SA, Vanhaecke L. 2016. Mass Spectrometric Mapping of the DNA Adductome as a Means to Study Genotoxin Exposure, Metabolism, and Effect ANALYTICAL CHEMISTRY, 88 :7436-7446 >DOI >Link DaPieve C, Sahgal N, Moore SA, Velasco-Garcia MN. 2013. Development of a liquid chromatography tandem mass spectrometry method to investigate the presence of biomarkers of DNA damage in urine related to red meat consumption and risk of colorectal cancer Rapid Communications in Mass Spectrometry, 21 :2493-2503 Vanden Bussche J, Moore SA, Pasmans F, Kuhnle GGC, Vanhaecke L. 2012. An approach based on ultra-high pressure liquid chromatography-tandem mass spectrometry to quantify O-6-methyl and O-6-carboxymethylguanine DNA adducts in intestinal cell lines JOURNAL OF CHROMATOGRAPHY A, 1257 :25-33 >DOI >Link Cocks S, Moore SA, Murphy M. 2012. Mutation sequencing and atomic force microscopy of fibroblasts treated with malondialdehyde 22nd Biennial congress of the European Association for Cancer Research Cocks S, Moore SA, Murphy M. 2011. The effects of malondialdehyde on human foetal lung fibroblasts 7th NCRI Cancer Conference Sanin R, Riby P, Wainwright M, Moore S. 2016. The determination of iron and manganese species in drinking water by LC-ICPMS Biennial Atomic Spectroscopy Symposium 2016 Cocks S, Moore SA, Murphy M. 2012. Mutation sequencing and atomic force microscopy of fibroblasts treated with malondialdehyde 22nd Biennial congress of the European Association for Cancer Research Cocks S, Moore SA, Murphy M. 2011. The effects of malondialdehyde on human foetal lung fibroblasts 7th NCRI Cancer Conference Vanden Bussche J, De Brabander H, Moore SA, Pasmans F, Van De Wiele T, Vanhaecke L. 2011. Do gastrointestinal bacteria affect the (geno)toxic activity of different meats? 13th Gut Day Symposium Moore SA, Velasco-Garcia M, Da Pieve C. 2010. Screening for colorectal cancer risk biomarkers related to diet Nutrition, Physical Activity & Cancer Prevention: Current Challenges, New Horizons, World cancer Research Fund, An international two-day Conference on Science and Policy Moore SA, Cocks S, Murphy M. 2010. The effects of malondialdehyde on the cell viability of human foetal lung fibroblasts A89, NCRI 6th Annual Cancer Conference Moore SA, Velasco MN, Sahgal N, Shuker DEG. 2009. Biosensor technology for the screening of cancer risk biomarkers related to diet EuroAnalysis 2009 Moore SA, Shuker DEG, Bingham SA. 2008. Development Of Analytical Methods To Determine The Product-Precursor Relationship Between Glycine And The DNA Adduct O6 Carboxymethyldeoxyguanosine 6. S. A. Moore, D. E. G. Shuker and S. A. Bingham, LJMU Institute for Health Research Annual Conference Moore SA, Shuker DEG, Velasco-Garcia MN, Sahgal N. 2008. Biosensor Assay Development For A Biomarker Of Colorectal Cancer: The DNA Adduct O6 Carboxymethyldeoxyguanosine British Association for Cancer Research; Pre-clinical Models: Biomarkers and Targeted Therapy Moore SA, Shuker DEG, Bingham SA. 2007. Is glycine a precursor of the DNA adduct O6 carboxymethyldeoxyguanosine? Development of analytical methods for a 13C-labelled volunteer study 98th AACR Annual Meeting Moore SA. 2007. Development Of Analytical Methods To Determine The Product-Precursor Relationship Between Glycine And The DNA Adduct O6 Carboxymethyldeoxyguanosine RSC Nucleic Acids Symposium Moore SA, Shuker DEG, Bingham SA. 2007. Is Glycine A Precursor Of The Dna Adduct O6 Carboxymethyldeoxyguanosine? Development Of Analytical Methods For A Volunteer Study Using 13C-Labelling. Diet And Cancer; Susceptibility, Prevention And Therapy Moore SA, Mason NJ, Smialek MA, Folkard M, Hoffman SV. 2006. Probing radiation damage at the molecular level 23rd Summer School and International Symposium on Physics of Ionized Gases :3-14 Shuker DEG, Ponnada S, Burns PA, Xu YZ, Moore SA. 2006. The origins and significance of O6-carboxymethylguanine as a mispairing lesion in DNA 97th AACR Annual Meeting Moore SA, Shuker DEG, Humphreys E, Bingham SA, Friesen MD. 2004. Dietary n-6 PUFA Does Not Influence Blood Levels of Malondialdehyde or Malondialdehyde-deoxyguanosine (M1dG) Adducts in Human Subjects 95th AACR Annual Meeting Shafaei Arvajeh M, Riby P, Sanin R, Moore S, Wainwright M. Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) in the analysis of manganese and iron in discoloured water Biennal National Atomic Spectroscopy Symposium/Trace Spec Hemeryck LY, Moore SA, Vanhaecke L. 2016. Mass Spectrometric Mapping of the DNA Adductome as a Means to Study Genotoxin Exposure, Metabolism, and Effect ANALYTICAL CHEMISTRY, 88 :7436-7446 >DOI >Link Vanden Bussche J, Hemeryck L, Van Hecke T, Kuhnle GGC, Pasmans F, Moore SA, Van de Wiele T, De Smet S, Vanhaecke L. 2014. O6-carboxymethylguanine DNA adduct formation and lipid peroxidation upon in vitro gastrointestinal digestion of haem-rich meat Molecular Nutrition & Food Research, DaPieve C, Sahgal N, Moore SA, Velasco-Garcia MN. 2013. Development of a liquid chromatography tandem mass spectrometry method to investigate the presence of biomarkers of DNA damage in urine related to red meat consumption and risk of colorectal cancer Rapid Communications in Mass Spectrometry, 21 :2493-2503 Vanden Bussche J, Moore SA, Pasmans F, Kuhnle GGC, Vanhaecke L. 2012. An approach based on ultra-high pressure liquid chromatography-tandem mass spectrometry to quantify O-6-methyl and O-6-carboxymethylguanine DNA adducts in intestinal cell lines JOURNAL OF CHROMATOGRAPHY A, 1257 :25-33 >DOI >Link