Louhelainen, Jari - Liverpool John Moores University - School of Pharmacy and Biomolecular Sciences

个人简介

Biography Dr Jari Louhelainen is a Senior Lecturer in Molecular Biology at LJMU, as well as Associate Professor of Biochemistry at University of Helsinki, one of the world’s top universities. He has two major lines of research – mammalian/medical genetics and forensics. In the past Dr. Louhelainen has worked for University of Oxford, Cancer Research UK, Karolinska Institute in Sweden and University of Helsinki in Finland. His research interests are gene expression systems, cDNA microarrays bioinformatics, genotyping and Single-Nucleotide Polymorphisms analysis, mutation analysis and DNA sequencing, human cell culture techniques, wildlife forensics and forensic/scientific photography. Jari Louhelainen has over 30 refereed publications, 2 edited books and one of which he has solely authored. He is a member of Royal Photographic Society Scientific and Medical Groups. He has also acted as an editor and editor-in-chief for scientific, peer-reviewed publications. During 2014-2015 he has given more than 30 seminars all over the world and has appeared frequently at national TV channels including those of USA, UK, and most European countries. He has also been a guest in numerous TV-programmes, including BBC Crimewatch Roadshow, BBC Breakfast Show, CNN, Al-Jazeera, ITV and full-length TV documentaries. Recently his work has been featured in numerous newspapers and magazines all over the world, including many leading scientific magazines in Europe. Languages English Finnish Swedish Degrees 2000 Karolinska Institute, Sweden PhD (Genetic Epidemiology) 1988 University of Helsinki, Finland MSc (Biochemistry) Languages Finnish Swedish English Degrees 2000, Karolinska Institute, Sweden, PhD 1988, University of Helsinki, Finland, MSc

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Louhelainen J. 2016. SNP Arrays. Microarrays (Basel), 5 >DOI >Link Joo CH, Allan R, Drust B, Close GL, Jeong TS, Bartlett JD, Mawhinney C, Louhelainen J, Morton JP, Gregson W. 2016. Passive and post-exercise cold-water immersion augments PGC-1 alpha and VEGF expression in human skeletal muscle EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 116 :2315-2326 >DOI >Link Jeong TS, Bartlett JD, Joo CH, Louhelainen J, Close GL, Morton JP, Drust B. 2015. Acute simulated soccer-specific training increases PGC-1α mRNA expression in human skeletal muscle Journal of Sports Sciences, 33 :1493-1503 >DOI Jeong T-S, Bartlett JD, Joo C-H, Louhelainen J, Close GL, Morton JP, Drust B. 2015. Acute simulated soccer-specific training increases PGC-1 alpha mRNA expression in human skeletal muscle JOURNAL OF SPORTS SCIENCES, 33 :1493-1503 >DOI >Link Bartlett JD, Louhelainen J, Iqbal Z, Cochran AJ, Gibala MJ, Gregson W, Close GL, Drust B, Morton JP. 2013. Reduced carbohydrate availability enhances exercise-induced p53 signaling in human skeletal muscle: implications for mitochondrial biogenesis. Am J Physiol Regul Integr Comp Physiol, 304 :R450-R458 >DOI >Link Taylor C, Bartlett JD, van de Graaf CS, Louhelainen J, Coyne V, Iqbal Z, Maclaren DPM, Gregson W, Close GL, Morton JP. 2013. Protein ingestion does not impair exercise-induced AMPK signalling when in a glycogen-depleted state: implications for train-low compete-high. Eur J Appl Physiol, 113 :1457-1468 >DOI >Link Cobley JN, Bartlett JD, Kayani A, Murray SW, Louhelainen J, Donovan T, Waldron S, Gregson W, Burniston JG, Morton JP, Close GL. 2012. PGC-1α transcriptional response and mitochondrial adaptation to acute exercise is maintained in skeletal muscle of sedentary elderly males. Biogerontology, 13 :621-631 >DOI >Link Cobley JN, Bartlett JD, Gregson W, Burniston JG, Morton JP, Close GL, Kayani A, Murray SW, Louhelainen J, Donovan T, Waldron S. 2012. PGC-1α transcriptional response and mitochondrial adaptation to acute exercise is maintained in skeletal muscle of sedentary elderly males Biogerontology, :1-11 >DOI Bartlett JD, Joo CH, Jeong TS, Louhelainen J, Cochran AJ, Gibala MJ, Gregson W, Close GL, Drust B, Morton JP. 2012. Matched work high-intensity interval and continuous running induce similar increases in PGC-1α mRNA, AMPK, p38 and p53 phosphorylation in human skeletal muscle Journal of Applied Physiology, 112 :1125-1143 >DOI Hampson C, Louhelainen J, McColl S. 2011. An RNA expression method for aging forensic hair samples. J Forensic Sci, 56 :359-365 >DOI >Link Louhelainen JP, Hurst CD, Pitt E, Nishiyama H, Pickett HA, Knowles MA. 2006. DBC1 re-expression alters the expression of multiple components of the plasminogen pathway. Oncogene, 25 :2409-2419 >DOI >Link Wild PJ, Krieg RC, Seidl J, Stoehr R, Reher K, Hofmann C, Louhelainen J, Rosenthal A, Hartmann A, Pilarsky C, Bosserhoff AK, Knuechel R. 2005. RNA expression profiling of normal and tumor cells following photodynamic therapy with 5-aminolevulinic acid-induced protoporphyrin IX in vitro. Mol Cancer Ther, 4 :516-528 >DOI >Link Natrajan R, Louhelainen J, Williams S, Laye J, Knowles MA. 2003. High-resolution deletion mapping of 15q13.2-q21.1 in transitional cell carcinoma of the bladder. Cancer Res, 63 :7657-7662 >Link Louhelainen J, Gill J, Hornigold N, Pitt E, Knowles MA. 2001. cDNA microarray analysis of transfected bladder cancer cell lines BRITISH JOURNAL OF CANCER, 85 :75-75 >Link Natrajan R, Louhelainen J, Knowles MA. 2001. Loss of heterozygosity at a common region of deletion on 15q14-q15.2 in transitional cell carcinomas. BRITISH JOURNAL OF CANCER, 85 :74-74 >Link Kimura F, Florl AR, Seifert HH, Louhelainen J, Maas S, Knowles MA, Schulz WA. 2001. Destabilization of chromosome 9 in transitional cell carcinoma of the urinary bladder. Br J Cancer, 85 :1887-1893 >DOI >Link Försti A, Louhelainen J, Söderberg M, Wijkström H, Hemminki K. 2001. Loss of heterozygosity in tumour-adjacent normal tissue of breast and bladder cancer. Eur J Cancer, 37 :1372-1380 >Link Wada T, Louhelainen J, Hemminki K, Adolfsson J, Wijkström H, Norming U, Borgström E, Hansson J, Steineck G. 2001. The prevalence of loss of heterozygosity in chromosome 3, including FHIT, in bladder cancer, using the fluorescent multiplex polymerase chain reaction. BJU Int, 87 :876-881 >Link Louhelainen J, Wijkström H, Hemminki K. 2001. Multiple regions with allelic loss at chromosome 3 in superficial multifocal bladder tumors. Int J Oncol, 18 :203-210 >Link Louhelainen J, Wijkström H, Hemminki K. 2000. Allelic losses demonstrate monoclonality of multifocal bladder tumors. Int J Cancer, 87 :522-527 >Link Louhelainen J, Wijkström H, Hemminki K. 2000. Initiation-development modelling of allelic losses on chromosome 9 in multifocal bladder cancer. Eur J Cancer, 36 :1441-1451 >Link Wada T, Louhelainen J, Hemminki K, Adolfsson J, Wijkström H, Norming U, Borgström E, Hansson J, Sandstedt B, Steineck G. 2000. Bladder cancer: allelic deletions at and around the retinoblastoma tumor suppressor gene in relation to stage and grade. Clin Cancer Res, 6 :610-615 >Link Szyfter K, Szmeja Z, Szyfter W, Hemminki K, Banaszewski J, Jaskuła-Sztul R, Louhelainen J. 1999. Molecular and cellular alterations in tobacco smoke-associated larynx cancer. Mutat Res, 445 :259-274 >Link Louhelainen J, Lindström E, Hemminki K, Toftgård R. 1998. Dinucleotide repeat polymorphism within the tumor suppressor gene PTCH at 9q22. Clin Genet, 54 :239-241 >Link Kumar R, Lundh Rozell B, Louhelainen J, Hemminki K. 1998. Mutations in the CDKN2A (p16INK4a) gene in microdissected sporadic primary melanomas. Int J Cancer, 75 :193-198 >Link