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个人简介

I began my career in 1983 as a part time lecturer and demonstrator whilst completing a pre-doctoral appointment fro British Petroleum. Concurrently whilst lecturing, I went to complete a part -time PhD in "Inhibition of lipid autoxidation in amphipathic systems". In 1989 I took up a Monsanto research fellowship at Reading University with Dr. Neal Stuart Isaacs at the High pressure research Unit. In 1991 I was appointed as a senior lecturer in Spectroscopy and Medicinal and Organic Chemistry at Hatfield polytechnic which became the University of Hertfordshire shortly thereafter. After a decade I moved to LJMU where I became a Subject leader in medicinal chemistry (until 2005).

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Javed S, Oise IE, Nahar L, Ismail FMD, Mahmood Z, Sarker SD. 2016. Isolation, Identification and Antiproliferative Activity of Triterpenes from the Genus Monotheca A. DC. RECORDS OF NATURAL PRODUCTS, 10 :782-787 >Link Lambert DJ, Parikh N, Messham SJ, Edwards G, Hieu VT, Dempster NM, Drew MGB, Nahar L, Sarker SD, Ismail FMD. 2015. One-pot synthesis and negative ion mass spectrometric investigation of a densely functionalized cinnoline TETRAHEDRON LETTERS, 56 :6980-6983 >DOI >Link Oliveira FM, Barbosa LCA, Ismail FMD. 2014. The diverse pharmacology and medicinal chemistry of phosphoramidates-a review RSC Advances, 4 :18998-19012 >DOI Ismail FMD, Geocze KC, Barbosa LCA, Fidencio PH, Silverio FO, Lima CF, Barbosa MCA. 2013. Essential oils from pequi fruits from the Brazilian Cerrado ecosystem FOOD RESEARCH INTERNATIONAL, 54 :1-8 >DOI Geőcze KC, Barbosa LCA, Fidêncio PH, Silvério FO, Lima CF, Barbosa MCA, Ismail FMD. 2013. Essential Volatile oils from pequi fruits from the Brazilian Cerrado ecosystem Food Research International, 54 Green C, Ismail F. 2012. Why you still need to know about micelles Pharmaceutical Journal, 289 :344-345 Montanari RM, Barbosa LCA, Demuner AJ, Silva CJ, Andrade NJ, Ismail FMD, Barbosa MCA. 2012. Exposure to Anacardiaceae volatile oils and their constituents induces lipid peroxidation within food-borne bacteria cells. Molecules, 17 :9728-9740 >DOI >Link Ismail FMD, Dascombe MJ, Drew MGB. 2009. Modulation of drug pharmacokinetics and pharmacodynamics by fluorine substitution Chimica Oggi Chemistry Today, 27 :16-20 Barbosa LCA, Maltha CRA, Cusati RC, Teixeira RR, Rodrigues FF, Silva AA, Drew MGB, Ismail FMD. 2009. Synthesis and Biological Evaluation of New Ozonides with Improved Plant Growth Regulatory Activity JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 57 :10107-10115 >DOI >Link Ismail FMD, Levitsky DO, Dembitsky VM. 2009. Aziridine alkaloids as potential therapeutic agents EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 44 :3373-3387 >DOI >Link Silva CJ, Barbosa LCA, Maltha URA, Pinheiro AL, Ismail FMD. 2007. Comparative study of the essential oils of seven Meialeuca (Myrtaceae) species grown in Brazil FLAVOUR AND FRAGRANCE JOURNAL, 22 :474-478 >DOI >Link Drew MGB, Metcalfe J, Dascombe MJ, Ismail FMD. 2007. De novo identification and stability of the artemisinin pharmacophore: Studies of the reductive decomposition of deoxyartemisinins and deoxyarteethers and the implications for the mode of antimalarial action JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 823 :34-46 >DOI >Link Almeida Barbosa LC, Demuner AJ, Clemente AD, de Paula VF, Ismail FMD. 2007. Seasonal variation in the composition of volatile oils from Schinus terebinthifolius raddi QUIMICA NOVA, 30 :1959-1965 >Link Teixeira RR, Barbosa LCA, Santana JO, Veloso DP, Ellena J, Doriguetto AC, Drew MGB, Ismail FMD. 2007. Synthesis and structural characterization of two nostoclide analogues JOURNAL OF MOLECULAR STRUCTURE, 837 :197-205 >DOI >Link Drew MGB, Metcalfe J, Dascombe MJ, Ismail FMD. 2006. Reactions of artemisinin and arteether with acid: Implications for stability and mode of antimalarial action JOURNAL OF MEDICINAL CHEMISTRY, 49 :6065-6073 >DOI >Link Denisov E, Denisova T, Ismail F. 2005. Intramolecular reactions of free radicals formed from artemisinin INTERNATIONAL JOURNAL OF CHEMICAL KINETICS, 37 :554-565 >DOI Drew MGB, Metcalfe J, Ismail FMD. 2005. Antimalarial drugs based on artemisinin: DFT calculations on the principal reactions JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 756 :87-95 >DOI >Link Dascombe MJ, Drew MGB, Morris H, Wilairat P, Auparakkitanon S, Moule WA, Alizadeh-Shekalgourabi S, Evans PG, Lloyd M, Dyas AM, Carr P, Ismail FMD. 2005. Mapping antimalarial pharmacophores as a useful tool for the rapid discovery of drugs effective in vivo: Design, construction, characterization, and pharmacology of metaquine JOURNAL OF MEDICINAL CHEMISTRY, 48 :5423-5436 >DOI >Link El-Sayed MS, Younesian A, Rahman K, Ismail FM, El-Sayed Ali Z. 2004. The effects of arm cranking exercise and training on platelet aggregation in male spinal cord individuals. Thromb Res, 113 :129-136 >DOI >Link Drew MGB, Metcalfe J, Ismail FMD. 2004. A DFT study of free radicals formed from artemisinin and related compounds JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 711 :95-105 >DOI >Link Ismail FMD. 2002. Important fluorinated drugs in experimental and clinical use JOURNAL OF FLUORINE CHEMISTRY, 118 :27-33 >DOI >Link Manzel L, Strekowski L, FMD I, Smith JC, Macfarlane DE. 1999. Antagonism of immunostimulatory CpG-oligodeoxynucleotides by 4-aminoquinolines and other weak bases: Mechanistic studies JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 291 :1337-1347 Yusof F, Audley BG, FMD I, Walker JM. 1998. Rapid Assay for the Incorporation of Isopentyl Diphosphate in Rubber Biosynthesis Journal of Rubber Research, 1 :48-66 Yusof F, Audley BG, FMD I, Walker JM. 1998. Rapid Assay for the Incorporation of Isopentyl Diphosphate in Rubber Biosynthesis Journal of Rubber Research, 1 :48-66 FMD I, Dascombe MJ, Carr P, SAM M, Rouault P. 1998. Novel aryl-bis-quinolines with antimalarial activity in-vivo JOURNAL OF PHARMACY AND PHARMACOLOGY, 50 :483-492

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